Aurora kinase A inhibition plus Tumor Treating Fields suppress glioma cell proliferation in a cilium-independent manner

Aurora kinase A inhibition plus Tumor Treating Fields suppress glioma cell proliferation in a cilium-independent manner

Tumor Treating Fields (TTFields) extend the survival of glioblastoma (GBM) patients by interfering with a broad range of tumor cellular processes. Among these, TTFields disrupt primary cilia stability on GBM cells. Here we asked if concomitant treatment of TTFields with other agents that interfere w...

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Bibliographic Details
Main Authors: Jia Tian, Julianne C. Mallinger, Ping Shi, Dahao Ling, Loic P. Deleyrolle, Min Lin, Habibeh Khoshbouei, Matthew R. Sarkisian
Format: Article
Language:English
Published: Elsevier 2024-07-01
Series:Translational Oncology
Subjects:
Tumor Treating Fields
AURKA
AURKB
Primary cilium
Autophagy
ARL13B
Online Access:http://www.sciencedirect.com/science/article/pii/S1936523324000834

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