The long noncoding RNA MEG3 regulates Ras-MAPK pathway through RASA1 in trophoblast and is associated with unexplained recurrent spontaneous abortion

The long noncoding RNA MEG3 regulates Ras-MAPK pathway through RASA1 in trophoblast and is associated with unexplained recurrent spontaneous abortion

Abstract Background Maternally Expressed Gene 3 (MEG3) is expressed at low levels in placental villi during preeclampsia; however, its roles in unexplained recurrent spontaneous abortion (URSA) remain unclear. In this study, we aimed to explore the relationship between MEG3 and URSA. Methods The dif...

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Bibliographic Details
Main Authors: Jun Zhang, Xinqiong Liu, Yali Gao
Format: Article
Language:English
Published: BMC 2021-07-01
Series:Molecular Medicine
Subjects:
URSA
MEG3
RASA1
RAS-MAPK pathway
Online Access:https://doi.org/10.1186/s10020-021-00337-9

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