Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes after Zinc and Anti-oxidant Therapy
Aim To assess serum Cu/Zn SOD (Superoxide Dismutase) concentration in individuals with clinical depression. Subjects and Methods Serum from 36 individuals diagnosed with clinical depression and 18 healthy controls were tested for Cu/Zn SOD serum concentration using ELISAs. Results Serum Cu/Zn SOD le...
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| Format: | Article |
| Language: | English |
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SAGE Publishing
2010-01-01
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| Series: | Nutrition and Metabolic Insights |
| Online Access: | https://doi.org/10.4137/NMI.S5044 |
| _version_ | 1811330714264666112 |
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| author | A.J. Russo |
| author_facet | A.J. Russo |
| author_sort | A.J. Russo |
| collection | DOAJ |
| description | Aim To assess serum Cu/Zn SOD (Superoxide Dismutase) concentration in individuals with clinical depression. Subjects and Methods Serum from 36 individuals diagnosed with clinical depression and 18 healthy controls were tested for Cu/Zn SOD serum concentration using ELISAs. Results Serum Cu/Zn SOD levels of depressed individuals (both with and without secondary anxiety) were significantly higher than age and gender similar controls. We also found that, post anti-oxidant therapy, Cu/Zn SOD levels normalized to the level of normal healthy controls. Discussion These results suggest an association between Cu/Zn SOD serum levels and clinical depression. |
| first_indexed | 2024-04-13T16:07:49Z |
| format | Article |
| id | doaj.art-57f27a12cede4ad4be5347b70e9136eb |
| institution | Directory Open Access Journal |
| issn | 1178-6388 |
| language | English |
| last_indexed | 2024-04-13T16:07:49Z |
| publishDate | 2010-01-01 |
| publisher | SAGE Publishing |
| record_format | Article |
| series | Nutrition and Metabolic Insights |
| spelling | doaj.art-57f27a12cede4ad4be5347b70e9136eb2022-12-22T02:40:21ZengSAGE PublishingNutrition and Metabolic Insights1178-63882010-01-01310.4137/NMI.S5044Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes after Zinc and Anti-oxidant TherapyA.J. Russo0Health Research Institute/Pfeiffer Treatment Center, 4575 Weaver Parkway, Warrenville, Illinois 60555.Aim To assess serum Cu/Zn SOD (Superoxide Dismutase) concentration in individuals with clinical depression. Subjects and Methods Serum from 36 individuals diagnosed with clinical depression and 18 healthy controls were tested for Cu/Zn SOD serum concentration using ELISAs. Results Serum Cu/Zn SOD levels of depressed individuals (both with and without secondary anxiety) were significantly higher than age and gender similar controls. We also found that, post anti-oxidant therapy, Cu/Zn SOD levels normalized to the level of normal healthy controls. Discussion These results suggest an association between Cu/Zn SOD serum levels and clinical depression.https://doi.org/10.4137/NMI.S5044 |
| spellingShingle | A.J. Russo Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes after Zinc and Anti-oxidant Therapy Nutrition and Metabolic Insights |
| title | Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes after Zinc and Anti-oxidant Therapy |
| title_full | Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes after Zinc and Anti-oxidant Therapy |
| title_fullStr | Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes after Zinc and Anti-oxidant Therapy |
| title_full_unstemmed | Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes after Zinc and Anti-oxidant Therapy |
| title_short | Increased Serum Cu/Zn SOD in Individuals with Clinical Depression Normalizes after Zinc and Anti-oxidant Therapy |
| title_sort | increased serum cu zn sod in individuals with clinical depression normalizes after zinc and anti oxidant therapy |
| url | https://doi.org/10.4137/NMI.S5044 |
| work_keys_str_mv | AT ajrusso increasedserumcuznsodinindividualswithclinicaldepressionnormalizesafterzincandantioxidanttherapy |