Factor XIII deficiency in a neonate presenting as subpial haemorrhage

Subpial haemorrhage is a rare cause of seizures in term neonates. A 3-day-old male infant, born at term with no history of perinatal hypoxia, presented with seizures and unremarkable physical examination in the interictal state. Imaging demonstrated left temporal subpial haemorrhage with the classic...

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Main Authors: Monish G. Karthikeyan, Poojitha Ronda, Prabhu C. Sugumaran
Format: Article
Language:English
Published: AOSIS 2022-05-01
Series:South African Journal of Radiology
Subjects:
Online Access:https://sajr.org.za/index.php/sajr/article/view/2344
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author Monish G. Karthikeyan
Poojitha Ronda
Prabhu C. Sugumaran
author_facet Monish G. Karthikeyan
Poojitha Ronda
Prabhu C. Sugumaran
author_sort Monish G. Karthikeyan
collection DOAJ
description Subpial haemorrhage is a rare cause of seizures in term neonates. A 3-day-old male infant, born at term with no history of perinatal hypoxia, presented with seizures and unremarkable physical examination in the interictal state. Imaging demonstrated left temporal subpial haemorrhage with the classic ‘yin-yang sign’ on MRI. The patient was subsequently diagnosed with factor XIII deficiency. Follow-up at 6 months and 12 months revealed encephalomalacia in the previous haemorrhagic areas with normal developmental milestones.
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spelling doaj.art-57f6bb86f05346a8a58d79657cf584e62022-12-22T02:37:13ZengAOSISSouth African Journal of Radiology1027-202X2078-67782022-05-01261e1e410.4102/sajr.v26i1.23441190Factor XIII deficiency in a neonate presenting as subpial haemorrhageMonish G. Karthikeyan0Poojitha Ronda1Prabhu C. Sugumaran2Department of Radiodiagnosis, Mahatma Gandhi Medical College and Research Institute, PondicherryDepartment of Radiodiagnosis, Mahatma Gandhi Medical College and Research Institute, PondicherryDepartment of Radiodiagnosis, Mahatma Gandhi Medical College and Research Institute, PondicherrySubpial haemorrhage is a rare cause of seizures in term neonates. A 3-day-old male infant, born at term with no history of perinatal hypoxia, presented with seizures and unremarkable physical examination in the interictal state. Imaging demonstrated left temporal subpial haemorrhage with the classic ‘yin-yang sign’ on MRI. The patient was subsequently diagnosed with factor XIII deficiency. Follow-up at 6 months and 12 months revealed encephalomalacia in the previous haemorrhagic areas with normal developmental milestones.https://sajr.org.za/index.php/sajr/article/view/2344intracranial haemorrhagesubpial haemorrhageterm neonateyin-yang sign factor xiiictmri
spellingShingle Monish G. Karthikeyan
Poojitha Ronda
Prabhu C. Sugumaran
Factor XIII deficiency in a neonate presenting as subpial haemorrhage
South African Journal of Radiology
intracranial haemorrhage
subpial haemorrhage
term neonate
yin-yang sign factor xiii
ct
mri
title Factor XIII deficiency in a neonate presenting as subpial haemorrhage
title_full Factor XIII deficiency in a neonate presenting as subpial haemorrhage
title_fullStr Factor XIII deficiency in a neonate presenting as subpial haemorrhage
title_full_unstemmed Factor XIII deficiency in a neonate presenting as subpial haemorrhage
title_short Factor XIII deficiency in a neonate presenting as subpial haemorrhage
title_sort factor xiii deficiency in a neonate presenting as subpial haemorrhage
topic intracranial haemorrhage
subpial haemorrhage
term neonate
yin-yang sign factor xiii
ct
mri
url https://sajr.org.za/index.php/sajr/article/view/2344
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