Polysaccharide-Based Nanomedicines Targeting Lung Cancer
A primary illness that accounts for a significant portion of fatalities worldwide is cancer. Among the main malignancies, lung cancer is recognised as the most chronic kind of cancer around the globe. Radiation treatment, surgery, and chemotherapy are some medical procedures used in the traditional...
| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-12-01
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| Series: | Pharmaceutics |
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| Online Access: | https://www.mdpi.com/1999-4923/14/12/2788 |
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| author | Asif Ahmad Bhat Gaurav Gupta Khalid Saad Alharbi Obaid Afzal Abdulmalik S. A. Altamimi Waleed Hassan Almalki Imran Kazmi Fahad A. Al-Abbasi Sami I. Alzarea Dinesh Kumar Chellappan Sachin Kumar Singh Ronan MacLoughlin Brian G Oliver Kamal Dua |
| author_facet | Asif Ahmad Bhat Gaurav Gupta Khalid Saad Alharbi Obaid Afzal Abdulmalik S. A. Altamimi Waleed Hassan Almalki Imran Kazmi Fahad A. Al-Abbasi Sami I. Alzarea Dinesh Kumar Chellappan Sachin Kumar Singh Ronan MacLoughlin Brian G Oliver Kamal Dua |
| author_sort | Asif Ahmad Bhat |
| collection | DOAJ |
| description | A primary illness that accounts for a significant portion of fatalities worldwide is cancer. Among the main malignancies, lung cancer is recognised as the most chronic kind of cancer around the globe. Radiation treatment, surgery, and chemotherapy are some medical procedures used in the traditional care of lung cancer. However, these methods lack selectivity and damage nearby healthy cells. Several polysaccharide-based nanomaterials have been created to transport chemotherapeutics to reduce harmful and adverse side effects and improve response during anti-tumour reactions. To address these drawbacks, a class of naturally occurring polymers called polysaccharides have special physical, chemical, and biological characteristics. They can interact with the immune system to induce a better immunological response. Furthermore, because of the flexibility of their structures, it is possible to create multifunctional nanocomposites with excellent stability and bioavailability for the delivery of medicines to tumour tissues. This study seeks to present new views on the use of polysaccharide-based chemotherapeutics and to highlight current developments in polysaccharide-based nanomedicines for lung cancer. |
| first_indexed | 2024-03-09T15:58:19Z |
| format | Article |
| id | doaj.art-57f89de155fb47a2ae9266d1908bf8a3 |
| institution | Directory Open Access Journal |
| issn | 1999-4923 |
| language | English |
| last_indexed | 2024-03-09T15:58:19Z |
| publishDate | 2022-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pharmaceutics |
| spelling | doaj.art-57f89de155fb47a2ae9266d1908bf8a32023-11-24T17:22:02ZengMDPI AGPharmaceutics1999-49232022-12-011412278810.3390/pharmaceutics14122788Polysaccharide-Based Nanomedicines Targeting Lung CancerAsif Ahmad Bhat0Gaurav Gupta1Khalid Saad Alharbi2Obaid Afzal3Abdulmalik S. A. Altamimi4Waleed Hassan Almalki5Imran Kazmi6Fahad A. Al-Abbasi7Sami I. Alzarea8Dinesh Kumar Chellappan9Sachin Kumar Singh10Ronan MacLoughlin11Brian G Oliver12Kamal Dua13School and of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Mahal Road, Jaipur 302017, IndiaSchool and of Pharmacy, Suresh Gyan Vihar University, Jagatpura, Mahal Road, Jaipur 302017, IndiaDepartment of Pharmacology, College of Pharmacy, Jouf University, Sakaka 72388, Saudi ArabiaDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al Kharj 11942, Saudi ArabiaDepartment of Pharmaceutical Chemistry, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al Kharj 11942, Saudi ArabiaDepartment of Pharmacology, College of Pharmacy, Umm Al-Qura University, Makkah 21955, Saudi ArabiaDepartment of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi ArabiaDepartment of Biochemistry, Faculty of Science, King Abdulaziz University, Jeddah 21589, Saudi ArabiaDepartment of Pharmacology, College of Pharmacy, Jouf University, Sakaka 72388, Saudi ArabiaDepartment of Life Sciences, School of Pharmacy, International Medical University, Bukit Jalil, Kuala Lumpur 57000, MalaysiaSchool of Pharmaceutical Sciences, Lovely Professional University, Phagwara, Punjab 144411, IndiaResearch and Development, Science and Emerging Technologies, Aerogen, IDA Business Park, Dangan, H91 HE94 Galway, IrelandSchool of Life Sciences, Faculty of Science, University of Technology, Sydney, NSW 2007, AustraliaFaculty of Health, Australian Research Centre in Complementary and Integrative Medicine, University of Technology Sydney, Ultimo, NSW 2007, AustraliaA primary illness that accounts for a significant portion of fatalities worldwide is cancer. Among the main malignancies, lung cancer is recognised as the most chronic kind of cancer around the globe. Radiation treatment, surgery, and chemotherapy are some medical procedures used in the traditional care of lung cancer. However, these methods lack selectivity and damage nearby healthy cells. Several polysaccharide-based nanomaterials have been created to transport chemotherapeutics to reduce harmful and adverse side effects and improve response during anti-tumour reactions. To address these drawbacks, a class of naturally occurring polymers called polysaccharides have special physical, chemical, and biological characteristics. They can interact with the immune system to induce a better immunological response. Furthermore, because of the flexibility of their structures, it is possible to create multifunctional nanocomposites with excellent stability and bioavailability for the delivery of medicines to tumour tissues. This study seeks to present new views on the use of polysaccharide-based chemotherapeutics and to highlight current developments in polysaccharide-based nanomedicines for lung cancer.https://www.mdpi.com/1999-4923/14/12/2788lung cancerpolysaccharidenanomedicinesimmunitychemotherapy |
| spellingShingle | Asif Ahmad Bhat Gaurav Gupta Khalid Saad Alharbi Obaid Afzal Abdulmalik S. A. Altamimi Waleed Hassan Almalki Imran Kazmi Fahad A. Al-Abbasi Sami I. Alzarea Dinesh Kumar Chellappan Sachin Kumar Singh Ronan MacLoughlin Brian G Oliver Kamal Dua Polysaccharide-Based Nanomedicines Targeting Lung Cancer Pharmaceutics lung cancer polysaccharide nanomedicines immunity chemotherapy |
| title | Polysaccharide-Based Nanomedicines Targeting Lung Cancer |
| title_full | Polysaccharide-Based Nanomedicines Targeting Lung Cancer |
| title_fullStr | Polysaccharide-Based Nanomedicines Targeting Lung Cancer |
| title_full_unstemmed | Polysaccharide-Based Nanomedicines Targeting Lung Cancer |
| title_short | Polysaccharide-Based Nanomedicines Targeting Lung Cancer |
| title_sort | polysaccharide based nanomedicines targeting lung cancer |
| topic | lung cancer polysaccharide nanomedicines immunity chemotherapy |
| url | https://www.mdpi.com/1999-4923/14/12/2788 |
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