Inherited thrombophilia and venous thromboembolism: testing rules in clinical practice
Testing for inherited thrombophilia in patients with venous thromboembolism is one of the most common genetic testing options prescribed by clinicians. Despite the large evidence base for the relationship of hereditary hemostasis disorders with the risk of venous thrombosis, most patients should not...
| Main Authors: | , |
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| Format: | Article |
| Language: | Russian |
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«FIRMA «SILICEA» LLC
2020-09-01
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| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/4024 |
| _version_ | 1797856749339803648 |
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| author | I. V. Zotova D. A. Zateyshchikov |
| author_facet | I. V. Zotova D. A. Zateyshchikov |
| author_sort | I. V. Zotova |
| collection | DOAJ |
| description | Testing for inherited thrombophilia in patients with venous thromboembolism is one of the most common genetic testing options prescribed by clinicians. Despite the large evidence base for the relationship of hereditary hemostasis disorders with the risk of venous thrombosis, most patients should not be tested. Performing tests in the acute phase of thrombosis or during anticoagulant therapy leads to erroneous results. The choice of anticoagulant therapy regimen and its duration are not specified by the presence of hereditary thrombophilia. The test results can be useful for increasing medication adherence of patient, determining the cause of thrombosis, especially at a young age or in atypical localization. |
| first_indexed | 2024-04-09T20:45:35Z |
| format | Article |
| id | doaj.art-57fb7bc4f6c94678a01fede64aa2c37a |
| institution | Directory Open Access Journal |
| issn | 1560-4071 2618-7620 |
| language | Russian |
| last_indexed | 2024-04-09T20:45:35Z |
| publishDate | 2020-09-01 |
| publisher | «FIRMA «SILICEA» LLC |
| record_format | Article |
| series | Российский кардиологический журнал |
| spelling | doaj.art-57fb7bc4f6c94678a01fede64aa2c37a2023-03-29T21:23:36Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202020-09-01253S10.15829/1560-4071-2020-40243005Inherited thrombophilia and venous thromboembolism: testing rules in clinical practiceI. V. Zotova0D. A. Zateyshchikov1Central State Medical Academy, Administrative Directorate of the President of the Russian Federation; City Clinical Hospital № 17Central State Medical Academy, Administrative Directorate of the President of the Russian Federation; City Clinical Hospital № 51Testing for inherited thrombophilia in patients with venous thromboembolism is one of the most common genetic testing options prescribed by clinicians. Despite the large evidence base for the relationship of hereditary hemostasis disorders with the risk of venous thrombosis, most patients should not be tested. Performing tests in the acute phase of thrombosis or during anticoagulant therapy leads to erroneous results. The choice of anticoagulant therapy regimen and its duration are not specified by the presence of hereditary thrombophilia. The test results can be useful for increasing medication adherence of patient, determining the cause of thrombosis, especially at a young age or in atypical localization.https://russjcardiol.elpub.ru/jour/article/view/4024venous thromboembolisminherited thrombophiliaanticoagulants |
| spellingShingle | I. V. Zotova D. A. Zateyshchikov Inherited thrombophilia and venous thromboembolism: testing rules in clinical practice Российский кардиологический журнал venous thromboembolism inherited thrombophilia anticoagulants |
| title | Inherited thrombophilia and venous thromboembolism: testing rules in clinical practice |
| title_full | Inherited thrombophilia and venous thromboembolism: testing rules in clinical practice |
| title_fullStr | Inherited thrombophilia and venous thromboembolism: testing rules in clinical practice |
| title_full_unstemmed | Inherited thrombophilia and venous thromboembolism: testing rules in clinical practice |
| title_short | Inherited thrombophilia and venous thromboembolism: testing rules in clinical practice |
| title_sort | inherited thrombophilia and venous thromboembolism testing rules in clinical practice |
| topic | venous thromboembolism inherited thrombophilia anticoagulants |
| url | https://russjcardiol.elpub.ru/jour/article/view/4024 |
| work_keys_str_mv | AT ivzotova inheritedthrombophiliaandvenousthromboembolismtestingrulesinclinicalpractice AT dazateyshchikov inheritedthrombophiliaandvenousthromboembolismtestingrulesinclinicalpractice |