Investigating Pathogenetic Mechanisms of Alzheimer’s Disease by Systems Biology Approaches for Drug Discovery

Investigating Pathogenetic Mechanisms of Alzheimer’s Disease by Systems Biology Approaches for Drug Discovery

Alzheimer’s disease (AD) is the most common cause of dementia, characterized by progressive cognitive decline and neurodegenerative disorder. Abnormal aggregations of intracellular neurofibrillary tangles (NFTs) and unusual accumulations of extracellular amyloid-β (Aβ) peptides are two important pat...

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Bibliographic Details
Main Authors: Shan-Ju Yeh, Ming-Hsun Chung, Bor-Sen Chen
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:International Journal of Molecular Sciences
Subjects:
Alzheimer’s disease
genetic and epigenetic networks
systems biology
drug discovery
Online Access:https://www.mdpi.com/1422-0067/22/20/11280

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