Understanding the complexities of space anaemia in extended space missions: revelations from microgravitational odyssey
Space travel exposes astronauts to several environmental challenges, including microgravity and radiation exposure. To overcome these stressors, the body undergoes various adaptations such as cardiovascular deconditioning, fluid shifts, metabolic changes, and alterations in the state of the bone mar...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2024-03-01
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| Series: | Frontiers in Physiology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fphys.2024.1321468/full |
| _version_ | 1827318256422092800 |
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| author | Edouard Lansiaux Nityanand Jain Swarali Yatin Chodnekar Abdelmomen Siddiq Muiz Ibrahim Mathieu Yèche Mathieu Yèche Inara Kantane |
| author_facet | Edouard Lansiaux Nityanand Jain Swarali Yatin Chodnekar Abdelmomen Siddiq Muiz Ibrahim Mathieu Yèche Mathieu Yèche Inara Kantane |
| author_sort | Edouard Lansiaux |
| collection | DOAJ |
| description | Space travel exposes astronauts to several environmental challenges, including microgravity and radiation exposure. To overcome these stressors, the body undergoes various adaptations such as cardiovascular deconditioning, fluid shifts, metabolic changes, and alterations in the state of the bone marrow. Another area of concern is the potential impact of these adaptations on erythrocyte and haemoglobin concentrations, which can lead to what is commonly referred to as space anaemia or microgravity-induced anaemia. It is known that anaemia may result in impaired physical and cognitive performance, making early detection and management crucial for the health and wellbeing of astronauts during extended space missions. However, the effects and mechanisms of space anaemia are not fully understood, and research is underway to determine the extent to which it poses a challenge to astronauts. Further research is needed to clarify the long-term effects of microgravity on the circulatory system and to investigate possible solutions to address spaceflight-induced anaemia. This article reviews the potential link between spaceflight and anaemia, based on existing evidence from simulated studies (e.g., microgravity and radiation studies) and findings from spaceflight studies (e.g., International Space Station and space shuttle missions). |
| first_indexed | 2024-04-24T23:56:02Z |
| format | Article |
| id | doaj.art-5800bcb976d1438dbe9f940e8c7b0e2b |
| institution | Directory Open Access Journal |
| issn | 1664-042X |
| language | English |
| last_indexed | 2024-04-24T23:56:02Z |
| publishDate | 2024-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Physiology |
| spelling | doaj.art-5800bcb976d1438dbe9f940e8c7b0e2b2024-03-14T12:18:28ZengFrontiers Media S.A.Frontiers in Physiology1664-042X2024-03-011510.3389/fphys.2024.13214681321468Understanding the complexities of space anaemia in extended space missions: revelations from microgravitational odysseyEdouard Lansiaux0Nityanand Jain1Swarali Yatin Chodnekar2Abdelmomen Siddiq3Muiz Ibrahim4Mathieu Yèche5Mathieu Yèche6Inara Kantane7Faculty of Medicine, Lille University School of Medicine, Lille, FranceStatistics Unit, Riga Stradinš University, Riga, LatviaFaculty of Medicine, Teaching University Geomedi LLC, Tbilisi, GeorgiaFaculty of Pharmacy, Mansoura University, Mansoura, EgyptDepartment of Public Health, International Higher School of Medicine, Bishkek, KyrgyzstanInstitut du Cerveau et de la Moelle épinière, Paris Brain Institute, Hopital de la Pitie-Salpetriere, Sorbonne Universite, INSERM U1127, CNRS UMR7225, Paris, FranceDépartement de Biologie de l’École Normale Supérieure (ENS), PSL Research University, Paris, FranceStatistics Unit, Riga Stradinš University, Riga, LatviaSpace travel exposes astronauts to several environmental challenges, including microgravity and radiation exposure. To overcome these stressors, the body undergoes various adaptations such as cardiovascular deconditioning, fluid shifts, metabolic changes, and alterations in the state of the bone marrow. Another area of concern is the potential impact of these adaptations on erythrocyte and haemoglobin concentrations, which can lead to what is commonly referred to as space anaemia or microgravity-induced anaemia. It is known that anaemia may result in impaired physical and cognitive performance, making early detection and management crucial for the health and wellbeing of astronauts during extended space missions. However, the effects and mechanisms of space anaemia are not fully understood, and research is underway to determine the extent to which it poses a challenge to astronauts. Further research is needed to clarify the long-term effects of microgravity on the circulatory system and to investigate possible solutions to address spaceflight-induced anaemia. This article reviews the potential link between spaceflight and anaemia, based on existing evidence from simulated studies (e.g., microgravity and radiation studies) and findings from spaceflight studies (e.g., International Space Station and space shuttle missions).https://www.frontiersin.org/articles/10.3389/fphys.2024.1321468/fullanaemiaspaceflightspace explorationhaemolysismicrogravityradiation |
| spellingShingle | Edouard Lansiaux Nityanand Jain Swarali Yatin Chodnekar Abdelmomen Siddiq Muiz Ibrahim Mathieu Yèche Mathieu Yèche Inara Kantane Understanding the complexities of space anaemia in extended space missions: revelations from microgravitational odyssey Frontiers in Physiology anaemia spaceflight space exploration haemolysis microgravity radiation |
| title | Understanding the complexities of space anaemia in extended space missions: revelations from microgravitational odyssey |
| title_full | Understanding the complexities of space anaemia in extended space missions: revelations from microgravitational odyssey |
| title_fullStr | Understanding the complexities of space anaemia in extended space missions: revelations from microgravitational odyssey |
| title_full_unstemmed | Understanding the complexities of space anaemia in extended space missions: revelations from microgravitational odyssey |
| title_short | Understanding the complexities of space anaemia in extended space missions: revelations from microgravitational odyssey |
| title_sort | understanding the complexities of space anaemia in extended space missions revelations from microgravitational odyssey |
| topic | anaemia spaceflight space exploration haemolysis microgravity radiation |
| url | https://www.frontiersin.org/articles/10.3389/fphys.2024.1321468/full |
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