L4/5 Disc Herniation: Not Unusually Accompanied with L5/S1 Low‐Grade Spondylolytic Spondylolisthesis
Objective Isthmic spondylolisthesis (IS) is distinguished by a congenital defect or acquired fracture of the pars interarticularis. Numerous studies on L5 low‐grade IS have been carried out; however, there is a paucity of data regarding the condition of L5 IS concomitant with L4/5 disc herniation. T...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2024-02-01
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| Series: | Orthopaedic Surgery |
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| Online Access: | https://doi.org/10.1111/os.13984 |
| _version_ | 1797335251184254976 |
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| author | Haicheng Zhou Qingshuang Zhou Bin Wang Yong Qiu Zezhang Zhu Zhen Liu Xu Sun |
| author_facet | Haicheng Zhou Qingshuang Zhou Bin Wang Yong Qiu Zezhang Zhu Zhen Liu Xu Sun |
| author_sort | Haicheng Zhou |
| collection | DOAJ |
| description | Objective Isthmic spondylolisthesis (IS) is distinguished by a congenital defect or acquired fracture of the pars interarticularis. Numerous studies on L5 low‐grade IS have been carried out; however, there is a paucity of data regarding the condition of L5 IS concomitant with L4/5 disc herniation. This study aimed to identify the incidence rate and to illustrate the possible risk factors for L4/5 disc herniation in L5 low‐grade IS patients. Methods A total of 268 consecutive patients diagnosed as L5/S1 low‐grade IS between May 2017 and May 2022 were retrospectively enrolled in this study. Depending on the presence of L4/5 disc herniation or not, patients were divided into an L4/5 disc herniation group (L4/5 DH) and an L4/5 non‐disc herniation group (L4/5 non‐DH). Radiographic parameters were measured, and the ratios of L4–S1 segmental lordosis (SL) to lumbar lordosis (LDI), L4 inferior endplate (IEP) to L5 superior endplate (SEP) (L4 IEP/L5 SEP), and L5 IEP to S1 SEP (L5 IEP/S1 SEP) were compared between groups. The Pfirrmann grade of the L4/5 disc and the L5/S1 disc, and Roussouly classifications of each patient were also recorded. Univariate analysis (including independent‐samples t‐test and χ2‐test) and multiple logistic regression analysis were performed to analyze the data. Results There were 40 patients (14.9%) in the L4/5 DH group. The Roussouly classification differed significantly between groups. As demonstrated by the Pfirrmann grade, the L4/5 DH group showed more advanced disc degeneration at L4/5 than the L4/5 non‐DH group. In contrast to the L4/5 non‐DH group, the L4/5 DH group had a significantly larger L4 IEP, L4 IEP/L5 SEP, S1 SEP, and LDI while smaller L4/5 disc angle, L4/5 disc height, slip percentage, lumbar lordosis, and sacral slope. Multivariate logistic regression analysis revealed that higher L4/5 disc Pfirrmann grade (p = 0.004), decreased L4/5 disc height (p < 0.001), and lower L5 slip percentage (p = 0.022) were significantly associated with the occurrence of L4/5 DH. Conclusions L4/5 disc herniation is not unusually accompanied by L5/S1 low‐grade IS. Advanced L4/5 disc degeneration, decreased L4/5 disc height, and lower L5 slip percentage might be significantly associated with L4/5 disc herniation. |
| first_indexed | 2024-03-08T08:34:15Z |
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| id | doaj.art-5802dc10acf544b8aeeef0d76d2d143e |
| institution | Directory Open Access Journal |
| issn | 1757-7853 1757-7861 |
| language | English |
| last_indexed | 2024-03-08T08:34:15Z |
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| series | Orthopaedic Surgery |
| spelling | doaj.art-5802dc10acf544b8aeeef0d76d2d143e2024-02-02T01:54:28ZengWileyOrthopaedic Surgery1757-78531757-78612024-02-0116244445110.1111/os.13984L4/5 Disc Herniation: Not Unusually Accompanied with L5/S1 Low‐Grade Spondylolytic SpondylolisthesisHaicheng Zhou0Qingshuang Zhou1Bin Wang2Yong Qiu3Zezhang Zhu4Zhen Liu5Xu Sun6Division of Spine Surgery, Department of Orthopedic Surgery Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University Nanjing ChinaDivision of Spine Surgery, Department of Orthopedic Surgery Nanjing Drum Tower Hospital Clinical College of Jiangsu University Nanjing ChinaDivision of Spine Surgery, Department of Orthopedic Surgery Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University Nanjing ChinaDivision of Spine Surgery, Department of Orthopedic Surgery Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University Nanjing ChinaDivision of Spine Surgery, Department of Orthopedic Surgery Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University Nanjing ChinaDivision of Spine Surgery, Department of Orthopedic Surgery Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University Nanjing ChinaDivision of Spine Surgery, Department of Orthopedic Surgery Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University Nanjing ChinaObjective Isthmic spondylolisthesis (IS) is distinguished by a congenital defect or acquired fracture of the pars interarticularis. Numerous studies on L5 low‐grade IS have been carried out; however, there is a paucity of data regarding the condition of L5 IS concomitant with L4/5 disc herniation. This study aimed to identify the incidence rate and to illustrate the possible risk factors for L4/5 disc herniation in L5 low‐grade IS patients. Methods A total of 268 consecutive patients diagnosed as L5/S1 low‐grade IS between May 2017 and May 2022 were retrospectively enrolled in this study. Depending on the presence of L4/5 disc herniation or not, patients were divided into an L4/5 disc herniation group (L4/5 DH) and an L4/5 non‐disc herniation group (L4/5 non‐DH). Radiographic parameters were measured, and the ratios of L4–S1 segmental lordosis (SL) to lumbar lordosis (LDI), L4 inferior endplate (IEP) to L5 superior endplate (SEP) (L4 IEP/L5 SEP), and L5 IEP to S1 SEP (L5 IEP/S1 SEP) were compared between groups. The Pfirrmann grade of the L4/5 disc and the L5/S1 disc, and Roussouly classifications of each patient were also recorded. Univariate analysis (including independent‐samples t‐test and χ2‐test) and multiple logistic regression analysis were performed to analyze the data. Results There were 40 patients (14.9%) in the L4/5 DH group. The Roussouly classification differed significantly between groups. As demonstrated by the Pfirrmann grade, the L4/5 DH group showed more advanced disc degeneration at L4/5 than the L4/5 non‐DH group. In contrast to the L4/5 non‐DH group, the L4/5 DH group had a significantly larger L4 IEP, L4 IEP/L5 SEP, S1 SEP, and LDI while smaller L4/5 disc angle, L4/5 disc height, slip percentage, lumbar lordosis, and sacral slope. Multivariate logistic regression analysis revealed that higher L4/5 disc Pfirrmann grade (p = 0.004), decreased L4/5 disc height (p < 0.001), and lower L5 slip percentage (p = 0.022) were significantly associated with the occurrence of L4/5 DH. Conclusions L4/5 disc herniation is not unusually accompanied by L5/S1 low‐grade IS. Advanced L4/5 disc degeneration, decreased L4/5 disc height, and lower L5 slip percentage might be significantly associated with L4/5 disc herniation.https://doi.org/10.1111/os.13984disc herniationincidencelow‐grade isthmic spondylolisthesisrisk factorssagittal alignment |
| spellingShingle | Haicheng Zhou Qingshuang Zhou Bin Wang Yong Qiu Zezhang Zhu Zhen Liu Xu Sun L4/5 Disc Herniation: Not Unusually Accompanied with L5/S1 Low‐Grade Spondylolytic Spondylolisthesis Orthopaedic Surgery disc herniation incidence low‐grade isthmic spondylolisthesis risk factors sagittal alignment |
| title | L4/5 Disc Herniation: Not Unusually Accompanied with L5/S1 Low‐Grade Spondylolytic Spondylolisthesis |
| title_full | L4/5 Disc Herniation: Not Unusually Accompanied with L5/S1 Low‐Grade Spondylolytic Spondylolisthesis |
| title_fullStr | L4/5 Disc Herniation: Not Unusually Accompanied with L5/S1 Low‐Grade Spondylolytic Spondylolisthesis |
| title_full_unstemmed | L4/5 Disc Herniation: Not Unusually Accompanied with L5/S1 Low‐Grade Spondylolytic Spondylolisthesis |
| title_short | L4/5 Disc Herniation: Not Unusually Accompanied with L5/S1 Low‐Grade Spondylolytic Spondylolisthesis |
| title_sort | l4 5 disc herniation not unusually accompanied with l5 s1 low grade spondylolytic spondylolisthesis |
| topic | disc herniation incidence low‐grade isthmic spondylolisthesis risk factors sagittal alignment |
| url | https://doi.org/10.1111/os.13984 |
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