Effects of different levels of fenofibrate on growth performance, carcase characteristics, abdominal fat, serum constitutes, immune system, caeca and microbial flora of broilers
So far, the effect of fenofibrate on the performance, quantitative and qualitative characteristics of broilers have not been investigated. For this reason, this study was performed to evaluate the effects of different levels of fenofibrate on the quantitative and qualitative characteristics of broil...
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| Format: | Article |
| Language: | English |
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Taylor & Francis Group
2022-12-01
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| Series: | Italian Journal of Animal Science |
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| Online Access: | http://dx.doi.org/10.1080/1828051X.2022.2032417 |
| _version_ | 1797737079540547584 |
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| author | Maryam Azizi Mehrdad Bouyeh Alireza Seidavi |
| author_facet | Maryam Azizi Mehrdad Bouyeh Alireza Seidavi |
| author_sort | Maryam Azizi |
| collection | DOAJ |
| description | So far, the effect of fenofibrate on the performance, quantitative and qualitative characteristics of broilers have not been investigated. For this reason, this study was performed to evaluate the effects of different levels of fenofibrate on the quantitative and qualitative characteristics of broilers in a completely randomised design with three treatments, four replicates and 10 one-day-old male Ross 308 strain chicks per replicate for 42 d. Experimental treatments included three levels of fenofibrate (0, 50 and 100 mgkg−1), which were used in combination with the basal diet. Results showed that 100 mgkg−1 fenofibrate in the diet increased the weight gain and European production efficiency factor (EPEF) and reduced feed intake and feed conversion ratio (FCR) of the whole period compared to the control (p < .05). The effect of experimental treatments on blood serum and immune system parameters other than spleen and bursal weights was not significant (p > .05). The number of E. coli, coliform and clostridium bacteria in the caecum decreased with the use of fenofibrate in comparison with the control group (p < .05), but fenofibrate increased the lactobacilli population in the caecum (p < .05). According to the results, the use of 100 mgkg−1 fenofibrate in the diet is recommended to improve some quantitative and qualitative characteristics of broilers.Highlights The accumulation of fat in the body of chickens is an undesirable trait for producers and consumers. Fenofibrate is a derivative of fibric acid and a blood fat-lowering chemical used to lower cholesterol levels in cardiovascular patients. The results of this study showed that the use of fenofibrate is effective in improving performance, and reducing the population of harmful bacteria in the gastrointestinal tract. |
| first_indexed | 2024-03-12T13:23:14Z |
| format | Article |
| id | doaj.art-5808591b0ffe4310b1029d8063b866ad |
| institution | Directory Open Access Journal |
| issn | 1594-4077 1828-051X |
| language | English |
| last_indexed | 2024-03-12T13:23:14Z |
| publishDate | 2022-12-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Italian Journal of Animal Science |
| spelling | doaj.art-5808591b0ffe4310b1029d8063b866ad2023-08-25T13:50:59ZengTaylor & Francis GroupItalian Journal of Animal Science1594-40771828-051X2022-12-0121134334910.1080/1828051X.2022.20324172032417Effects of different levels of fenofibrate on growth performance, carcase characteristics, abdominal fat, serum constitutes, immune system, caeca and microbial flora of broilersMaryam Azizi0Mehrdad Bouyeh1Alireza Seidavi2Department of Animal Science, Rasht Branch, Islamic Azad UniversityDepartment of Animal Science, Rasht Branch, Islamic Azad UniversityDepartment of Animal Science, Rasht Branch, Islamic Azad UniversitySo far, the effect of fenofibrate on the performance, quantitative and qualitative characteristics of broilers have not been investigated. For this reason, this study was performed to evaluate the effects of different levels of fenofibrate on the quantitative and qualitative characteristics of broilers in a completely randomised design with three treatments, four replicates and 10 one-day-old male Ross 308 strain chicks per replicate for 42 d. Experimental treatments included three levels of fenofibrate (0, 50 and 100 mgkg−1), which were used in combination with the basal diet. Results showed that 100 mgkg−1 fenofibrate in the diet increased the weight gain and European production efficiency factor (EPEF) and reduced feed intake and feed conversion ratio (FCR) of the whole period compared to the control (p < .05). The effect of experimental treatments on blood serum and immune system parameters other than spleen and bursal weights was not significant (p > .05). The number of E. coli, coliform and clostridium bacteria in the caecum decreased with the use of fenofibrate in comparison with the control group (p < .05), but fenofibrate increased the lactobacilli population in the caecum (p < .05). According to the results, the use of 100 mgkg−1 fenofibrate in the diet is recommended to improve some quantitative and qualitative characteristics of broilers.Highlights The accumulation of fat in the body of chickens is an undesirable trait for producers and consumers. Fenofibrate is a derivative of fibric acid and a blood fat-lowering chemical used to lower cholesterol levels in cardiovascular patients. The results of this study showed that the use of fenofibrate is effective in improving performance, and reducing the population of harmful bacteria in the gastrointestinal tract.http://dx.doi.org/10.1080/1828051X.2022.2032417fenofibrateimmune systemmicrofloraserum lipid parameters |
| spellingShingle | Maryam Azizi Mehrdad Bouyeh Alireza Seidavi Effects of different levels of fenofibrate on growth performance, carcase characteristics, abdominal fat, serum constitutes, immune system, caeca and microbial flora of broilers Italian Journal of Animal Science fenofibrate immune system microflora serum lipid parameters |
| title | Effects of different levels of fenofibrate on growth performance, carcase characteristics, abdominal fat, serum constitutes, immune system, caeca and microbial flora of broilers |
| title_full | Effects of different levels of fenofibrate on growth performance, carcase characteristics, abdominal fat, serum constitutes, immune system, caeca and microbial flora of broilers |
| title_fullStr | Effects of different levels of fenofibrate on growth performance, carcase characteristics, abdominal fat, serum constitutes, immune system, caeca and microbial flora of broilers |
| title_full_unstemmed | Effects of different levels of fenofibrate on growth performance, carcase characteristics, abdominal fat, serum constitutes, immune system, caeca and microbial flora of broilers |
| title_short | Effects of different levels of fenofibrate on growth performance, carcase characteristics, abdominal fat, serum constitutes, immune system, caeca and microbial flora of broilers |
| title_sort | effects of different levels of fenofibrate on growth performance carcase characteristics abdominal fat serum constitutes immune system caeca and microbial flora of broilers |
| topic | fenofibrate immune system microflora serum lipid parameters |
| url | http://dx.doi.org/10.1080/1828051X.2022.2032417 |
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