Evaluation of correlation between nucleated red blood cell count in term newborns and meconium-stained amniotic fluid
Considering the incidence of meconium-stained amniotic fluid (MSAF) in newborns and its complications, and also based on indirect reports pointing out relationship between nucleated red blood cell (nRBC), as a marker of chronic hypoxia, and MSAF in term newborns, and in order to determine this relat...
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| Format: | Article |
| Language: | fas |
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Tehran University of Medical Sciences
2001-09-01
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| Series: | Tehran University Medical Journal |
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| Online Access: | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5567.pdf&manuscript_id=5567 |
| _version_ | 1818353831732314112 |
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| author | Esmaeilian L Jahanfar M |
| author_facet | Esmaeilian L Jahanfar M |
| author_sort | Esmaeilian L |
| collection | DOAJ |
| description | Considering the incidence of meconium-stained amniotic fluid (MSAF) in newborns and its complications, and also based on indirect reports pointing out relationship between nucleated red blood cell (nRBC), as a marker of chronic hypoxia, and MSAF in term newborns, and in order to determine this relationship more accurately, this study was done on women with uncomplicated singleton term pregnancy that admitted for delivery at Shariati hospital in year 2000. After excluding confounding factors on nRBC, case group who includes infants with MSAF, and control group who have clear amniotic fluid were determined. Maternal age and parity, gestational age, birth weight, apgar score, neonatal out come, and FHR pattern as well as newborn hemoglobin values were evaluated. Venous cord blood was analyzed for nRBC counts per 100 WBC. Case and control groups were divided according to nRBC counts with cutoff point of 10 and then compared statistically. From the samples, 117 cases and 67 controls were evaluated. Maternal and neonatal factors were similar in two situations. Number of nRBC was 3.75±4.8 in control group and 12.04±11.7 in case group (P<0.01) and it was abnormal (>10) in 9 percent of newborns with clear fluid and 32 percent of MSAF (P<0.01). Cord blood nRBC count increased when meconium is passed intrauterine. This suggests that cases with MSAF may be at risk of chronic hypoxia. Cohort research is recommended to study the affect of delivery mode on the neonatal outcome in cases with MSAF and to evaluate the cause of fetal hypoxia in uncomplicated pregnancy with MSAF. |
| first_indexed | 2024-12-13T19:15:47Z |
| format | Article |
| id | doaj.art-5808cb0788b040b3bfd0cbd31fd7c263 |
| institution | Directory Open Access Journal |
| issn | 1683-1764 1735-7322 |
| language | fas |
| last_indexed | 2024-12-13T19:15:47Z |
| publishDate | 2001-09-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Tehran University Medical Journal |
| spelling | doaj.art-5808cb0788b040b3bfd0cbd31fd7c2632022-12-21T23:34:18ZfasTehran University of Medical SciencesTehran University Medical Journal1683-17641735-73222001-09-015942428Evaluation of correlation between nucleated red blood cell count in term newborns and meconium-stained amniotic fluidEsmaeilian LJahanfar MConsidering the incidence of meconium-stained amniotic fluid (MSAF) in newborns and its complications, and also based on indirect reports pointing out relationship between nucleated red blood cell (nRBC), as a marker of chronic hypoxia, and MSAF in term newborns, and in order to determine this relationship more accurately, this study was done on women with uncomplicated singleton term pregnancy that admitted for delivery at Shariati hospital in year 2000. After excluding confounding factors on nRBC, case group who includes infants with MSAF, and control group who have clear amniotic fluid were determined. Maternal age and parity, gestational age, birth weight, apgar score, neonatal out come, and FHR pattern as well as newborn hemoglobin values were evaluated. Venous cord blood was analyzed for nRBC counts per 100 WBC. Case and control groups were divided according to nRBC counts with cutoff point of 10 and then compared statistically. From the samples, 117 cases and 67 controls were evaluated. Maternal and neonatal factors were similar in two situations. Number of nRBC was 3.75±4.8 in control group and 12.04±11.7 in case group (P<0.01) and it was abnormal (>10) in 9 percent of newborns with clear fluid and 32 percent of MSAF (P<0.01). Cord blood nRBC count increased when meconium is passed intrauterine. This suggests that cases with MSAF may be at risk of chronic hypoxia. Cohort research is recommended to study the affect of delivery mode on the neonatal outcome in cases with MSAF and to evaluate the cause of fetal hypoxia in uncomplicated pregnancy with MSAF.http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5567.pdf&manuscript_id=5567Nucleated red blood cellMeconium-stained amniotic fluidTerm newborns |
| spellingShingle | Esmaeilian L Jahanfar M Evaluation of correlation between nucleated red blood cell count in term newborns and meconium-stained amniotic fluid Tehran University Medical Journal Nucleated red blood cell Meconium-stained amniotic fluid Term newborns |
| title | Evaluation of correlation between nucleated red blood cell count in term newborns and meconium-stained amniotic fluid |
| title_full | Evaluation of correlation between nucleated red blood cell count in term newborns and meconium-stained amniotic fluid |
| title_fullStr | Evaluation of correlation between nucleated red blood cell count in term newborns and meconium-stained amniotic fluid |
| title_full_unstemmed | Evaluation of correlation between nucleated red blood cell count in term newborns and meconium-stained amniotic fluid |
| title_short | Evaluation of correlation between nucleated red blood cell count in term newborns and meconium-stained amniotic fluid |
| title_sort | evaluation of correlation between nucleated red blood cell count in term newborns and meconium stained amniotic fluid |
| topic | Nucleated red blood cell Meconium-stained amniotic fluid Term newborns |
| url | http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/5567.pdf&manuscript_id=5567 |
| work_keys_str_mv | AT esmaeilianl evaluationofcorrelationbetweennucleatedredbloodcellcountintermnewbornsandmeconiumstainedamnioticfluid AT jahanfarm evaluationofcorrelationbetweennucleatedredbloodcellcountintermnewbornsandmeconiumstainedamnioticfluid |