Buprenorphine to reverse respiratory depression from methadone overdose in opioid-dependent patients: a prospective randomized trial

Buprenorphine to reverse respiratory depression from methadone overdose in opioid-dependent patients: a prospective randomized trial

Abstract Background Naloxone is the usual drug used in opioid-induced respiratory depression but it has a short half-life, precipitates withdrawal in dependent patients, and thus for persistent reversal of long-acting opioids has to be given by titrated doses and infusions. The partial agonist bupre...

Full description

Bibliographic Details
Main Authors: Nasim Zamani, Nicholas A. Buckley, Hossein Hassanian-Moghaddam
Format: Article
Language:English
Published: BMC 2020-02-01
Series:Critical Care
Subjects:
Opioid overdose
Antidote treatment
Methadone
Naloxone
Buprenorphine
Online Access:https://doi.org/10.1186/s13054-020-2740-y

Similar Items

Similar Items