Fabrication, Properties and Applications of Dense Hydroxyapatite: A Review
In the last five decades, there have been vast advances in the field of biomaterials, including ceramics, glasses, glass-ceramics and metal alloys. Dense and porous ceramics have been widely used for various biomedical applications. Current applications of bioceramics include bone grafts, spinal...
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| Format: | Article |
| Language: | English |
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MDPI AG
2015-12-01
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| Series: | Journal of Functional Biomaterials |
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| Online Access: | http://www.mdpi.com/2079-4983/6/4/1099 |
| _version_ | 1811308137541533696 |
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| author | Mythili Prakasam Janis Locs Kristine Salma-Ancane Dagnija Loca Alain Largeteau Liga Berzina-Cimdina |
| author_facet | Mythili Prakasam Janis Locs Kristine Salma-Ancane Dagnija Loca Alain Largeteau Liga Berzina-Cimdina |
| author_sort | Mythili Prakasam |
| collection | DOAJ |
| description | In the last five decades, there have been vast advances in the field of biomaterials, including ceramics, glasses, glass-ceramics and metal alloys. Dense and porous ceramics have been widely used for various biomedical applications. Current applications of bioceramics include bone grafts, spinal fusion, bone repairs, bone fillers, maxillofacial reconstruction, etc. Amongst the various calcium phosphate compositions, hydroxyapatite, which has a composition similar to human bone, has attracted wide interest. Much emphasis is given to tissue engineering, both in porous and dense ceramic forms. The current review focusses on the various applications of dense hydroxyapatite and other dense biomaterials on the aspects of transparency and the mechanical and electrical behavior. Prospective future applications, established along the aforesaid applications of hydroxyapatite, appear to be promising regarding bone bonding, advanced medical treatment methods, improvement of the mechanical strength of artificial bone grafts and better in vitro/in vivo methodologies to afford more particular outcomes. |
| first_indexed | 2024-04-13T09:17:38Z |
| format | Article |
| id | doaj.art-580f41d4e7dd401fbfb83819b654f203 |
| institution | Directory Open Access Journal |
| issn | 2079-4983 |
| language | English |
| last_indexed | 2024-04-13T09:17:38Z |
| publishDate | 2015-12-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Functional Biomaterials |
| spelling | doaj.art-580f41d4e7dd401fbfb83819b654f2032022-12-22T02:52:42ZengMDPI AGJournal of Functional Biomaterials2079-49832015-12-01641099114010.3390/jfb6041099jfb6041099Fabrication, Properties and Applications of Dense Hydroxyapatite: A ReviewMythili Prakasam0Janis Locs1Kristine Salma-Ancane2Dagnija Loca3Alain Largeteau4Liga Berzina-Cimdina5CNRS, Université de Bordeaux, ICMCB, 87 avenue du Dr. A. Schweitzer, Pessac F-33608, FranceRudolfs Cimdins Riga Biomaterials Innovations and Development Centre of RTU, Institute of General Chemical Engineering, Faculty of Materials Science and Applied Chemistry, Riga Technical University, Pulka 3, Riga LV-1007, LatviaRudolfs Cimdins Riga Biomaterials Innovations and Development Centre of RTU, Institute of General Chemical Engineering, Faculty of Materials Science and Applied Chemistry, Riga Technical University, Pulka 3, Riga LV-1007, LatviaRudolfs Cimdins Riga Biomaterials Innovations and Development Centre of RTU, Institute of General Chemical Engineering, Faculty of Materials Science and Applied Chemistry, Riga Technical University, Pulka 3, Riga LV-1007, LatviaCNRS, Université de Bordeaux, ICMCB, 87 avenue du Dr. A. Schweitzer, Pessac F-33608, FranceRudolfs Cimdins Riga Biomaterials Innovations and Development Centre of RTU, Institute of General Chemical Engineering, Faculty of Materials Science and Applied Chemistry, Riga Technical University, Pulka 3, Riga LV-1007, LatviaIn the last five decades, there have been vast advances in the field of biomaterials, including ceramics, glasses, glass-ceramics and metal alloys. Dense and porous ceramics have been widely used for various biomedical applications. Current applications of bioceramics include bone grafts, spinal fusion, bone repairs, bone fillers, maxillofacial reconstruction, etc. Amongst the various calcium phosphate compositions, hydroxyapatite, which has a composition similar to human bone, has attracted wide interest. Much emphasis is given to tissue engineering, both in porous and dense ceramic forms. The current review focusses on the various applications of dense hydroxyapatite and other dense biomaterials on the aspects of transparency and the mechanical and electrical behavior. Prospective future applications, established along the aforesaid applications of hydroxyapatite, appear to be promising regarding bone bonding, advanced medical treatment methods, improvement of the mechanical strength of artificial bone grafts and better in vitro/in vivo methodologies to afford more particular outcomes.http://www.mdpi.com/2079-4983/6/4/1099biomaterialsdense ceramicshydroxyapatitebioceramicsproperties |
| spellingShingle | Mythili Prakasam Janis Locs Kristine Salma-Ancane Dagnija Loca Alain Largeteau Liga Berzina-Cimdina Fabrication, Properties and Applications of Dense Hydroxyapatite: A Review Journal of Functional Biomaterials biomaterials dense ceramics hydroxyapatite bioceramics properties |
| title | Fabrication, Properties and Applications of Dense Hydroxyapatite: A Review |
| title_full | Fabrication, Properties and Applications of Dense Hydroxyapatite: A Review |
| title_fullStr | Fabrication, Properties and Applications of Dense Hydroxyapatite: A Review |
| title_full_unstemmed | Fabrication, Properties and Applications of Dense Hydroxyapatite: A Review |
| title_short | Fabrication, Properties and Applications of Dense Hydroxyapatite: A Review |
| title_sort | fabrication properties and applications of dense hydroxyapatite a review |
| topic | biomaterials dense ceramics hydroxyapatite bioceramics properties |
| url | http://www.mdpi.com/2079-4983/6/4/1099 |
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