Validation of a spectrophotometric method to estimate the adsorption on nanoemulsions of an antimalarial oligonucleotide

Validation of a spectrophotometric method to estimate the adsorption on nanoemulsions of an antimalarial oligonucleotide

This study describes the validation of a spectrophotometric method to estimate oligonucleotides association with cationic nanoemulsions. Phosphodiester and phosphorothioate oligonucleotides targeting Plasmodium falciparum topoisomerase II were analyzed at 262 nm. Linear response (r > 0.998) was o...

Full description

Bibliographic Details
Main Authors: Fernanda Bruxel, Silvia S Guterres, Helder F Teixeira
Format: Article
Language:English
Published: Sociedade Brasileira de Química 2011-09-01
Series:Química Nova
Subjects:
antimalarial oligonucleotides
nanoemulsions
UV analysis
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000900026&lng=en&tlng=en

Similar Items

Similar Items