Cardiovascular disease in Alpha 1 antitrypsin deficiency: an observational study assessing the role of neutrophil proteinase activity and the suitability of validated screening tools

Cardiovascular disease in Alpha 1 antitrypsin deficiency: an observational study assessing the role of neutrophil proteinase activity and the suitability of validated screening tools

Abstract Background Alpha 1 Antitrypsin Deficiency (AATD) is a rare, inherited lung disease which shares features with Chronic Obstructive Pulmonary Disease (COPD) but has a greater burden of proteinase related tissue damage. These proteinases are associated with cardiovascular disease (CVD) in the...

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Bibliographic Details
Main Authors:	E. Sapey, L. E. Crowley, R. G. Edgar, D. Griffiths, S. Samanta, H. Crisford, C. E. Bolton, J. R. Hurst, R. A. Stockley
Format:	Article
Language:	English
Published:	BMC 2024-03-01
Series:	Orphanet Journal of Rare Diseases
Subjects:	Cardiovascular disease Chronic obstructive pulmonary disease Emphysema Alpha 1 anti-trypsin deficiency Arterial stiffness Risk assessment
Online Access:	https://doi.org/10.1186/s13023-024-03124-x

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