Phenotypes of Myopathy-related Actin Mutants in differentiated C2C12 Myotubes

<p>Abstract</p> <p>Background</p> <p>About 20 % of nemaline myopathies are thus far related to skeletal muscle alpha-actin. Seven actin mutants located in different parts of the actin molecule and linked to different forms of the disease were selected and expressed as E...

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Bibliographic Details
Main Authors: Machesky Laura M, Rommelaere Heidi, Bathe Friederike S
Format: Article
Language:English
Published: BMC 2007-01-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/8/2