The Interaction of the Endogenous Hydrogen Sulfide and Oxytocin Systems in Fluid Regulation and the Cardiovascular System
The purpose of this review is to explore the parallel roles and interaction of hydrogen sulfide (H<sub>2</sub>S) and oxytocin (OT) in cardiovascular regulation and fluid homeostasis. Their interaction has been recently reported to be relevant during physical and psychological trauma. How...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-08-01
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| Series: | Antioxidants |
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| Online Access: | https://www.mdpi.com/2076-3921/9/8/748 |
| _version_ | 1797558225359339520 |
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| author | Nicole Denoix Oscar McCook Sarah Ecker Rui Wang Christiane Waller Peter Radermacher Tamara Merz |
| author_facet | Nicole Denoix Oscar McCook Sarah Ecker Rui Wang Christiane Waller Peter Radermacher Tamara Merz |
| author_sort | Nicole Denoix |
| collection | DOAJ |
| description | The purpose of this review is to explore the parallel roles and interaction of hydrogen sulfide (H<sub>2</sub>S) and oxytocin (OT) in cardiovascular regulation and fluid homeostasis. Their interaction has been recently reported to be relevant during physical and psychological trauma. However, literature reports on H<sub>2</sub>S in physical trauma and OT in psychological trauma are abundant, whereas available information regarding H<sub>2</sub>S in psychological trauma and OT in physical trauma is much more limited. This review summarizes recent direct and indirect evidence of the interaction of the two systems and their convergence in downstream nitric oxide-dependent signaling pathways during various types of trauma, in an effort to better understand biological correlates of psychosomatic interdependencies. |
| first_indexed | 2024-03-10T17:27:20Z |
| format | Article |
| id | doaj.art-5816bf1a00b2448ca9718a296886dcac |
| institution | Directory Open Access Journal |
| issn | 2076-3921 |
| language | English |
| last_indexed | 2024-03-10T17:27:20Z |
| publishDate | 2020-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antioxidants |
| spelling | doaj.art-5816bf1a00b2448ca9718a296886dcac2023-11-20T10:07:30ZengMDPI AGAntioxidants2076-39212020-08-019874810.3390/antiox9080748The Interaction of the Endogenous Hydrogen Sulfide and Oxytocin Systems in Fluid Regulation and the Cardiovascular SystemNicole Denoix0Oscar McCook1Sarah Ecker2Rui Wang3Christiane Waller4Peter Radermacher5Tamara Merz6Clinic for Psychosomatic Medicine and Psychotherapy, Ulm University Medical Center, 89081 Ulm, GermanyInstitute for Anesthesiological Pathophysiology and Process Engineering, Ulm University Medical Center, 89081 Ulm, GermanyInstitute for Anesthesiological Pathophysiology and Process Engineering, Ulm University Medical Center, 89081 Ulm, GermanyFaculty of Science, York University, Toronto, ON M3J 1P3, CanadaDepartment of Psychosomatic Medicine and Psychotherapy, Nuremberg General Hospital, Paracelsus Medical University, 90419 Nuremberg, GermanyInstitute for Anesthesiological Pathophysiology and Process Engineering, Ulm University Medical Center, 89081 Ulm, GermanyInstitute for Anesthesiological Pathophysiology and Process Engineering, Ulm University Medical Center, 89081 Ulm, GermanyThe purpose of this review is to explore the parallel roles and interaction of hydrogen sulfide (H<sub>2</sub>S) and oxytocin (OT) in cardiovascular regulation and fluid homeostasis. Their interaction has been recently reported to be relevant during physical and psychological trauma. However, literature reports on H<sub>2</sub>S in physical trauma and OT in psychological trauma are abundant, whereas available information regarding H<sub>2</sub>S in psychological trauma and OT in physical trauma is much more limited. This review summarizes recent direct and indirect evidence of the interaction of the two systems and their convergence in downstream nitric oxide-dependent signaling pathways during various types of trauma, in an effort to better understand biological correlates of psychosomatic interdependencies.https://www.mdpi.com/2076-3921/9/8/748cystathionine γ-lyasehydrogen sulfideoxytocin receptorpsychosomatic medicinecardiovascularfluid regulation |
| spellingShingle | Nicole Denoix Oscar McCook Sarah Ecker Rui Wang Christiane Waller Peter Radermacher Tamara Merz The Interaction of the Endogenous Hydrogen Sulfide and Oxytocin Systems in Fluid Regulation and the Cardiovascular System Antioxidants cystathionine γ-lyase hydrogen sulfide oxytocin receptor psychosomatic medicine cardiovascular fluid regulation |
| title | The Interaction of the Endogenous Hydrogen Sulfide and Oxytocin Systems in Fluid Regulation and the Cardiovascular System |
| title_full | The Interaction of the Endogenous Hydrogen Sulfide and Oxytocin Systems in Fluid Regulation and the Cardiovascular System |
| title_fullStr | The Interaction of the Endogenous Hydrogen Sulfide and Oxytocin Systems in Fluid Regulation and the Cardiovascular System |
| title_full_unstemmed | The Interaction of the Endogenous Hydrogen Sulfide and Oxytocin Systems in Fluid Regulation and the Cardiovascular System |
| title_short | The Interaction of the Endogenous Hydrogen Sulfide and Oxytocin Systems in Fluid Regulation and the Cardiovascular System |
| title_sort | interaction of the endogenous hydrogen sulfide and oxytocin systems in fluid regulation and the cardiovascular system |
| topic | cystathionine γ-lyase hydrogen sulfide oxytocin receptor psychosomatic medicine cardiovascular fluid regulation |
| url | https://www.mdpi.com/2076-3921/9/8/748 |
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