The incremental shuttle walk test predicts mortality in non-group 1 pulmonary hypertension: results from the ASPIRE Registry
Pulmonary hypertension (PH) is classified into five groups based on disease etiology but there is only limited information on the prognostic value of exercise testing in non-group 1 PH. In group 1 PH, the incremental shuttle walking test (ISWT) distance has been shown to correlate with pulmonary hem...
| Main Authors: | , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-05-01
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| Series: | Pulmonary Circulation |
| Online Access: | https://doi.org/10.1177/2045894019848649 |
| _version_ | 1811228877712785408 |
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| author | Catherine G. Billings Robert Lewis Judith A. Hurdman Robin Condliffe Charlie A. Elliot A.A. Roger Thompson Ian A. Smith Matthew Austin Iain J. Armstrong Neil Hamilton Athanasios Charalampopoulos Ian Sabroe Andrew J. Swift Alexander M. Rothman Jim M. Wild Allan Lawrie Judith C. Waterhouse David G. Kiely |
| author_facet | Catherine G. Billings Robert Lewis Judith A. Hurdman Robin Condliffe Charlie A. Elliot A.A. Roger Thompson Ian A. Smith Matthew Austin Iain J. Armstrong Neil Hamilton Athanasios Charalampopoulos Ian Sabroe Andrew J. Swift Alexander M. Rothman Jim M. Wild Allan Lawrie Judith C. Waterhouse David G. Kiely |
| author_sort | Catherine G. Billings |
| collection | DOAJ |
| description | Pulmonary hypertension (PH) is classified into five groups based on disease etiology but there is only limited information on the prognostic value of exercise testing in non-group 1 PH. In group 1 PH, the incremental shuttle walking test (ISWT) distance has been shown to correlate with pulmonary hemodynamics and predict survival without a ceiling effect. This study assessed the ISWT in non-group 1 PH. Data were retrieved from the ASPIRE Registry (Assessing the Spectrum of Pulmonary hypertension Identified at a REferral centre) for consecutive patients diagnosed with PH. Patients were required to have been systematically assessed as group 2–5 PH and to have a baseline ISWT within three months of cardiac catheterization. Patients were stratified according to incremental shuttle walk test distance (ISWD) and ISWT distance percent predicted (ISWD%pred). A total of 479 patients with non-group 1 PH were identified. ISWD and ISWD%pred correlated significantly with symptoms and hemodynamic severity. ISWD and ISWD%pred predicted survival with no ceiling effect. The test was prognostic in groups 2, 3, and 4. ISWD and ISWD%pred and change in ISWD and ISWD%pred at one year were all significant predictors of outcome. In patients with non-group 1 PH the ISWT is a simple non-invasive test that is easy to perform, is predictive of survival at baseline and follow-up, reflects change, and can be used in the assessment of PH of any etiology. |
| first_indexed | 2024-04-12T10:05:11Z |
| format | Article |
| id | doaj.art-5818b993517d4ff5a41fb5090e781b80 |
| institution | Directory Open Access Journal |
| issn | 2045-8940 |
| language | English |
| last_indexed | 2024-04-12T10:05:11Z |
| publishDate | 2019-05-01 |
| publisher | Wiley |
| record_format | Article |
| series | Pulmonary Circulation |
| spelling | doaj.art-5818b993517d4ff5a41fb5090e781b802022-12-22T03:37:28ZengWileyPulmonary Circulation2045-89402019-05-01910.1177/2045894019848649The incremental shuttle walk test predicts mortality in non-group 1 pulmonary hypertension: results from the ASPIRE RegistryCatherine G. Billings0Robert Lewis1Judith A. Hurdman2Robin Condliffe3Charlie A. Elliot4A.A. Roger Thompson5Ian A. Smith6Matthew Austin7Iain J. Armstrong8Neil Hamilton9Athanasios Charalampopoulos10Ian Sabroe11Andrew J. Swift12Alexander M. Rothman13Jim M. Wild14Allan Lawrie15Judith C. Waterhouse16David G. Kiely17Sheffield Pulmonary Vascular Disease Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UKDepartment of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Medical School, Sheffield, UKSheffield Pulmonary Vascular Disease Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UKSheffield Pulmonary Vascular Disease Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UKSheffield Pulmonary Vascular Disease Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UKDepartment of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Medical School, Sheffield, UKSheffield Pulmonary Vascular Disease Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UKSheffield Pulmonary Vascular Disease Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UKSheffield Pulmonary Vascular Disease Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UKSheffield Pulmonary Vascular Disease Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UKSheffield Pulmonary Vascular Disease Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UKDepartment of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Medical School, Sheffield, UKInsigneo Institute for Medicine, University of Sheffield, The Pam Liversidge Building, Sir Frederick Mappin Building, Sheffield, UKDepartment of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Medical School, Sheffield, UKInsigneo Institute for Medicine, University of Sheffield, The Pam Liversidge Building, Sir Frederick Mappin Building, Sheffield, UKDepartment of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Medical School, Sheffield, UKSheffield Pulmonary Vascular Disease Unit, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UKInsigneo Institute for Medicine, University of Sheffield, The Pam Liversidge Building, Sir Frederick Mappin Building, Sheffield, UKPulmonary hypertension (PH) is classified into five groups based on disease etiology but there is only limited information on the prognostic value of exercise testing in non-group 1 PH. In group 1 PH, the incremental shuttle walking test (ISWT) distance has been shown to correlate with pulmonary hemodynamics and predict survival without a ceiling effect. This study assessed the ISWT in non-group 1 PH. Data were retrieved from the ASPIRE Registry (Assessing the Spectrum of Pulmonary hypertension Identified at a REferral centre) for consecutive patients diagnosed with PH. Patients were required to have been systematically assessed as group 2–5 PH and to have a baseline ISWT within three months of cardiac catheterization. Patients were stratified according to incremental shuttle walk test distance (ISWD) and ISWT distance percent predicted (ISWD%pred). A total of 479 patients with non-group 1 PH were identified. ISWD and ISWD%pred correlated significantly with symptoms and hemodynamic severity. ISWD and ISWD%pred predicted survival with no ceiling effect. The test was prognostic in groups 2, 3, and 4. ISWD and ISWD%pred and change in ISWD and ISWD%pred at one year were all significant predictors of outcome. In patients with non-group 1 PH the ISWT is a simple non-invasive test that is easy to perform, is predictive of survival at baseline and follow-up, reflects change, and can be used in the assessment of PH of any etiology.https://doi.org/10.1177/2045894019848649 |
| spellingShingle | Catherine G. Billings Robert Lewis Judith A. Hurdman Robin Condliffe Charlie A. Elliot A.A. Roger Thompson Ian A. Smith Matthew Austin Iain J. Armstrong Neil Hamilton Athanasios Charalampopoulos Ian Sabroe Andrew J. Swift Alexander M. Rothman Jim M. Wild Allan Lawrie Judith C. Waterhouse David G. Kiely The incremental shuttle walk test predicts mortality in non-group 1 pulmonary hypertension: results from the ASPIRE Registry Pulmonary Circulation |
| title | The incremental shuttle walk test predicts mortality in non-group 1 pulmonary hypertension: results from the ASPIRE Registry |
| title_full | The incremental shuttle walk test predicts mortality in non-group 1 pulmonary hypertension: results from the ASPIRE Registry |
| title_fullStr | The incremental shuttle walk test predicts mortality in non-group 1 pulmonary hypertension: results from the ASPIRE Registry |
| title_full_unstemmed | The incremental shuttle walk test predicts mortality in non-group 1 pulmonary hypertension: results from the ASPIRE Registry |
| title_short | The incremental shuttle walk test predicts mortality in non-group 1 pulmonary hypertension: results from the ASPIRE Registry |
| title_sort | incremental shuttle walk test predicts mortality in non group 1 pulmonary hypertension results from the aspire registry |
| url | https://doi.org/10.1177/2045894019848649 |
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