COVID-19 Vaccination: Infectivity and Symptomaticity of SARS- COV-2 among residents in Bonny Island, Rivers State, Nigeria

Background: In December 2019, the severe acute respiratory syndrome Coronavirus 2 (SARS-COV-2) popularly called COVID-19 emerged. The disease is associated with asymptomatic, mild to severe respiratory symptoms. Use of Vaccine is essential in its control and in Bonny Island, the AstraZeneca chAdOx...

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Main Authors: Ogbondah BO, Owhonda G, Luke A, Jaja ID, Green P, Pius OM
Format: Article
Language:English
Published: Nigerian Medical Association, Akwa Ibom State Branch 2023-05-01
Series:Ibom Medical Journal
Subjects:
Online Access:https://ibommedicaljournal.org/index.php/imjhome/article/view/307
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author Ogbondah BO
Owhonda G
Luke A
Jaja ID
Green P
Pius OM
author_facet Ogbondah BO
Owhonda G
Luke A
Jaja ID
Green P
Pius OM
author_sort Ogbondah BO
collection DOAJ
description Background: In December 2019, the severe acute respiratory syndrome Coronavirus 2 (SARS-COV-2) popularly called COVID-19 emerged. The disease is associated with asymptomatic, mild to severe respiratory symptoms. Use of Vaccine is essential in its control and in Bonny Island, the AstraZeneca chAdOx 1 novel Coronavirus 2019 vaccine was used. Study objective is to determine the effectiveness of this vaccine in preventing infection and symptoms associated with the virus on residents of Bonny Island. Method: Study is a facility based cross-sectional study, conducted between May and October 2021, at General Hospital Bonny, a COVID 19 testing and vaccination center. Study population were respondents who had previously been vaccinated for Covid-19 that visited the facility for COVID-19 PCR test. All eligible respondents were enlisted into the study until the sample size of 623 was achieved. Interviewer administered questionnaire was used to collect information on socio-demographics and medical history including vaccination status. Multivariate regression analysis using SPSS version 21.0 was used to analyze data with statistical significance set at 0.05. Ethical clearance and permission for the study were granted by appropriate authority while informed consent was extracted from respondents. Result: There was statistically significant association between COVID-19 vaccination and negative COVID-19 PCR test result (OR 5.98), married couple and age (0-20 and 21-30 years the most and least compliant respectively). There was no significant relationship between symptoms associated with COVID-19 infection and vaccination status. Conclusion: COVID-19 vaccination uptake protects against COVID 19 infection but does not have any significant effect on symptoms associated with the infection. Married couple and respondents aged 0-20 years were more compliant to vaccine uptake.
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spelling doaj.art-581bbd7ff4f04c7aa8b75aeaf3e10a7b2024-03-06T11:55:27ZengNigerian Medical Association, Akwa Ibom State BranchIbom Medical Journal1597-71882735-99642023-05-0116210.61386/imj.v16i2.307COVID-19 Vaccination: Infectivity and Symptomaticity of SARS- COV-2 among residents in Bonny Island, Rivers State, NigeriaOgbondah BO0Owhonda G1Luke A2Jaja ID3Green P4Pius OM5Department of Community Medicine, College of Medicine, Rivers State University, Nkpolu Orowoukwo, Port Harcourt, Rivers State, NigeriaDepartment of Community Medicine, College of Medicine, Rivers State University, Nkpolu Orowoukwo, Port Harcourt, Rivers State, NigeriaDepartment of Community Medicine, College of Medicine, Rivers State University, Nkpolu Orowoukwo, Port Harcourt, Rivers State, NigeriaDepartment of Community Medicine, College of Medicine, Rivers State University, Nkpolu Orowoukwo, Port Harcourt, Rivers State, NigeriaDepartment of Community Medicine, College of Medicine, Rivers State University, Nkpolu Orowoukwo, Port Harcourt, Rivers State, NigeriaDepartment of Community Medicine, College of Medicine, River State University, Nkpolu Oroworukwo, Port Harcourt, Rivers State, Nigeria Background: In December 2019, the severe acute respiratory syndrome Coronavirus 2 (SARS-COV-2) popularly called COVID-19 emerged. The disease is associated with asymptomatic, mild to severe respiratory symptoms. Use of Vaccine is essential in its control and in Bonny Island, the AstraZeneca chAdOx 1 novel Coronavirus 2019 vaccine was used. Study objective is to determine the effectiveness of this vaccine in preventing infection and symptoms associated with the virus on residents of Bonny Island. Method: Study is a facility based cross-sectional study, conducted between May and October 2021, at General Hospital Bonny, a COVID 19 testing and vaccination center. Study population were respondents who had previously been vaccinated for Covid-19 that visited the facility for COVID-19 PCR test. All eligible respondents were enlisted into the study until the sample size of 623 was achieved. Interviewer administered questionnaire was used to collect information on socio-demographics and medical history including vaccination status. Multivariate regression analysis using SPSS version 21.0 was used to analyze data with statistical significance set at 0.05. Ethical clearance and permission for the study were granted by appropriate authority while informed consent was extracted from respondents. Result: There was statistically significant association between COVID-19 vaccination and negative COVID-19 PCR test result (OR 5.98), married couple and age (0-20 and 21-30 years the most and least compliant respectively). There was no significant relationship between symptoms associated with COVID-19 infection and vaccination status. Conclusion: COVID-19 vaccination uptake protects against COVID 19 infection but does not have any significant effect on symptoms associated with the infection. Married couple and respondents aged 0-20 years were more compliant to vaccine uptake. https://ibommedicaljournal.org/index.php/imjhome/article/view/307COVID-19vaccinationsymptoms
spellingShingle Ogbondah BO
Owhonda G
Luke A
Jaja ID
Green P
Pius OM
COVID-19 Vaccination: Infectivity and Symptomaticity of SARS- COV-2 among residents in Bonny Island, Rivers State, Nigeria
Ibom Medical Journal
COVID-19
vaccination
symptoms
title COVID-19 Vaccination: Infectivity and Symptomaticity of SARS- COV-2 among residents in Bonny Island, Rivers State, Nigeria
title_full COVID-19 Vaccination: Infectivity and Symptomaticity of SARS- COV-2 among residents in Bonny Island, Rivers State, Nigeria
title_fullStr COVID-19 Vaccination: Infectivity and Symptomaticity of SARS- COV-2 among residents in Bonny Island, Rivers State, Nigeria
title_full_unstemmed COVID-19 Vaccination: Infectivity and Symptomaticity of SARS- COV-2 among residents in Bonny Island, Rivers State, Nigeria
title_short COVID-19 Vaccination: Infectivity and Symptomaticity of SARS- COV-2 among residents in Bonny Island, Rivers State, Nigeria
title_sort covid 19 vaccination infectivity and symptomaticity of sars cov 2 among residents in bonny island rivers state nigeria
topic COVID-19
vaccination
symptoms
url https://ibommedicaljournal.org/index.php/imjhome/article/view/307
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