Drug Design Targeting the Muscarinic Receptors and the Implications in Central Nervous System Disorders

Drug Design Targeting the Muscarinic Receptors and the Implications in Central Nervous System Disorders

There is substantial evidence that cholinergic system function impairment plays a significant role in many central nervous system (CNS) disorders. During the past three decades, muscarinic receptors (mAChRs) have been implicated in various pathologies and have been prominent targets of drug-design e...

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Bibliographic Details
Main Authors: Chad R. Johnson, Brian D. Kangas, Emily M. Jutkiewicz, Jack Bergman, Andrew Coop
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biomedicines
Subjects:
Alzheimer’s disease
schizophrenia
depression
major depressive disorder
drug design
muscarinic receptors
Online Access:https://www.mdpi.com/2227-9059/10/2/398

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