E-cadherin binds to desmoglein to facilitate desmosome assembly

E-cadherin binds to desmoglein to facilitate desmosome assembly

Desmosomes are adhesive junctions composed of two desmosomal cadherins: desmocollin (Dsc) and desmoglein (Dsg). Previous studies demonstrate that E-cadherin (Ecad), an adhesive protein that interacts in both trans (between opposing cells) and cis (on the same cell surface) conformations, facilitates...

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Bibliographic Details
Main Authors: Omer Shafraz, Matthias Rübsam, Sara N Stahley, Amber L Caldara, Andrew P Kowalczyk, Carien M Niessen, Sanjeevi Sivasankar
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-07-01
Series:eLife
Subjects:
cell adhesion
desmosomes
cadherins
Online Access:https://elifesciences.org/articles/37629

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