Protection against ovariectomy-induced bone loss by tranilast.

BACKGROUND: Tranilast (N-(3',4'-dimethoxycinnamonyl) anthranilic acid) has been shown to be therapeutically effective, exerting anti-inflammatory and anti-oxidative effects via acting on macrophage. We hypothesized that Tranilast may protect against oxidative stress-induced bone loss via a...

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Bibliographic Details
Main Authors: Tien Van Phan, Ke Ke, Ok-Joo Sul, Yun-Kyung Park, Kack-Kyun Kim, Yeon-Soo Cho, Hun-Taeg Chung, Hye-Seon Choi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3994081?pdf=render