Sleep spindle deficits in antipsychotic-naïve early course schizophrenia and in non-psychotic first-degree relatives

Sleep spindle deficits in antipsychotic-naïve early course schizophrenia and in non-psychotic first-degree relatives

Introduction: Chronic medicated patients with schizophrenia have marked reductions in sleep spindle activity and a correlated deficit in sleep-dependent memory consolidation. Using archival data, we investigated whether antipsychotic-naïve early course patients with schizophrenia and young non-psyc...

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Main Authors: Dara S Manoach, Charmaine eDemanuele, Erin J. Wamsley, Mark eVangel, Debra M Montrose, Jean eMiewald, David eKupfer, Daniel eBuysse, Robert eStickgold, Matcheri S Keshavan
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-10-01
Series:Frontiers in Human Neuroscience
Subjects:
Cognition
Executive Function
Polysomnography
Schizophrenia
Sleep
antipsychotic
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnhum.2014.00762/full

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