Zoonotic RVA: State of the Art and Distribution in the Animal World
Rotavirus species A (RVA) is a pathogen mainly affecting children under five years old and young animals. The infection produces acute diarrhea in its hosts and, in intensively reared livestock animals, can cause severe economic losses. In this study, we analyzed all RVA genomic constellations descr...
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-11-01
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| Series: | Viruses |
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| Online Access: | https://www.mdpi.com/1999-4915/14/11/2554 |
| _version_ | 1797463820205031424 |
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| author | Ricardo Gabriel Díaz Alarcón Domingo Javier Liotta Samuel Miño |
| author_facet | Ricardo Gabriel Díaz Alarcón Domingo Javier Liotta Samuel Miño |
| author_sort | Ricardo Gabriel Díaz Alarcón |
| collection | DOAJ |
| description | Rotavirus species A (RVA) is a pathogen mainly affecting children under five years old and young animals. The infection produces acute diarrhea in its hosts and, in intensively reared livestock animals, can cause severe economic losses. In this study, we analyzed all RVA genomic constellations described in animal hosts. This review included animal RVA strains in humans. We compiled detection methods, hosts, genotypes and complete genomes. RVA was described in 86 animal species, with 52% (45/86) described by serology, microscopy or the hybridization method; however, strain sequences were not described. All of these reports were carried out between 1980 and 1990. In 48% (41/86) of them, 9251 strain sequences were reported, with 28% being porcine, 27% bovine, 12% equine and 33% from several other animal species. Genomic constellations were performed in 80% (32/40) of hosts. Typical constellation patterns were observed in groups such as birds, domestic animals and artiodactyls. The analysis of the constellations showed RVA’s capacity to infect a broad range of species, because there are RVA genotypes (even entire constellations) from animal species which were described in other studies. This suggests that this virus could generate highly virulent variants through gene reassortments and that these strains could be transmitted to humans as a zoonotic disease, making future surveillance necessary for the prevention of future outbreaks. |
| first_indexed | 2024-03-09T17:56:09Z |
| format | Article |
| id | doaj.art-5828b59bc65a405ea9ecb8bbcefa430c |
| institution | Directory Open Access Journal |
| issn | 1999-4915 |
| language | English |
| last_indexed | 2024-03-09T17:56:09Z |
| publishDate | 2022-11-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Viruses |
| spelling | doaj.art-5828b59bc65a405ea9ecb8bbcefa430c2023-11-24T10:19:06ZengMDPI AGViruses1999-49152022-11-011411255410.3390/v14112554Zoonotic RVA: State of the Art and Distribution in the Animal WorldRicardo Gabriel Díaz Alarcón0Domingo Javier Liotta1Samuel Miño2Laboratory of Applied Molecular Biology (LaBiMAp), Faculty of Exacts, Chemical and Natural Sciences, National University of Misiones (UNaM), Posadas 3300, Misiones, ArgentinaLaboratory of Applied Molecular Biology (LaBiMAp), Faculty of Exacts, Chemical and Natural Sciences, National University of Misiones (UNaM), Posadas 3300, Misiones, ArgentinaLaboratory of Applied Molecular Biology (LaBiMAp), Faculty of Exacts, Chemical and Natural Sciences, National University of Misiones (UNaM), Posadas 3300, Misiones, ArgentinaRotavirus species A (RVA) is a pathogen mainly affecting children under five years old and young animals. The infection produces acute diarrhea in its hosts and, in intensively reared livestock animals, can cause severe economic losses. In this study, we analyzed all RVA genomic constellations described in animal hosts. This review included animal RVA strains in humans. We compiled detection methods, hosts, genotypes and complete genomes. RVA was described in 86 animal species, with 52% (45/86) described by serology, microscopy or the hybridization method; however, strain sequences were not described. All of these reports were carried out between 1980 and 1990. In 48% (41/86) of them, 9251 strain sequences were reported, with 28% being porcine, 27% bovine, 12% equine and 33% from several other animal species. Genomic constellations were performed in 80% (32/40) of hosts. Typical constellation patterns were observed in groups such as birds, domestic animals and artiodactyls. The analysis of the constellations showed RVA’s capacity to infect a broad range of species, because there are RVA genotypes (even entire constellations) from animal species which were described in other studies. This suggests that this virus could generate highly virulent variants through gene reassortments and that these strains could be transmitted to humans as a zoonotic disease, making future surveillance necessary for the prevention of future outbreaks.https://www.mdpi.com/1999-4915/14/11/2554rotavirus Aconstellationsgenotypeexotic hostzoonotic |
| spellingShingle | Ricardo Gabriel Díaz Alarcón Domingo Javier Liotta Samuel Miño Zoonotic RVA: State of the Art and Distribution in the Animal World Viruses rotavirus A constellations genotype exotic host zoonotic |
| title | Zoonotic RVA: State of the Art and Distribution in the Animal World |
| title_full | Zoonotic RVA: State of the Art and Distribution in the Animal World |
| title_fullStr | Zoonotic RVA: State of the Art and Distribution in the Animal World |
| title_full_unstemmed | Zoonotic RVA: State of the Art and Distribution in the Animal World |
| title_short | Zoonotic RVA: State of the Art and Distribution in the Animal World |
| title_sort | zoonotic rva state of the art and distribution in the animal world |
| topic | rotavirus A constellations genotype exotic host zoonotic |
| url | https://www.mdpi.com/1999-4915/14/11/2554 |
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