Testis cell pyroptosis mediated by CASP1 and CASP4: possible sertoli cell-only syndrome pathogenesis

Testis cell pyroptosis mediated by CASP1 and CASP4: possible sertoli cell-only syndrome pathogenesis

Abstract Background Sertoli cell-only syndrome (SCOS) is the most serious pathological type of non-obstructive azoospermia. Recently, several genes related to SCOS have been identified, including FANCM, TEX14, NR5A1, NANOS2, PLK4, WNK3, and FANCA, but they cannot fully explain the pathogenesis of SC...

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Bibliographic Details
Main Authors: Wantao Liu, Xinan Li, Qiang Ma, Yongtong Zhu, Wenzhong Zhao, Yisheng Yang, Weiqiang Xiao, Daxiong Huang, Fengbo Cai, David Yiu Leung Chan, Shanchao Zhao, Qingjun Chu
Format: Article
Language:English
Published: BMC 2023-06-01
Series:Reproductive Biology and Endocrinology
Subjects:
Sertoli cell-only syndrome (SCOS)
CASP1
CASP4
Pyroptosis
Online Access:https://doi.org/10.1186/s12958-023-01101-w

Internet

https://doi.org/10.1186/s12958-023-01101-w

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