Epstein-Barr virus: general factors, virus-related diseases and measurement of viral load after transplant
The Epstein-Barr virus is responsible for infectious mononucleosis syndrome and is also closely associated to several types of cancer. The main complication involving Epstein-Barr virus infection, both in recipients of hematopoietic stem cells and solid organs, is post-transplant lymphoproliferative...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2011-10-01
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| Series: | Revista Brasileira de Hematologia e Hemoterapia |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842011000500016 |
| _version_ | 1818517904978608128 |
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| author | Luciana Cristina Fagundes Gequelin Irina N Riediger Sueli M Nakatani Alexander W Biondo Carmem M Bonfim |
| author_facet | Luciana Cristina Fagundes Gequelin Irina N Riediger Sueli M Nakatani Alexander W Biondo Carmem M Bonfim |
| author_sort | Luciana Cristina Fagundes Gequelin |
| collection | DOAJ |
| description | The Epstein-Barr virus is responsible for infectious mononucleosis syndrome and is also closely associated to several types of cancer. The main complication involving Epstein-Barr virus infection, both in recipients of hematopoietic stem cells and solid organs, is post-transplant lymphoproliferative disease. The importance of this disease has increased interest in the development of laboratory tools to improve post-transplant monitoring and to detect the disease before clinical evolution. Viral load analysis for Epstein-Barr virus through real-time polymerase chain reaction is, at present, the best tool to measure viral load. However, there is not a consensus on which sample type is the best for the test and what is its predictive value for therapeutic interventions. |
| first_indexed | 2024-12-11T01:02:36Z |
| format | Article |
| id | doaj.art-5833adeec3c146af9bbc0e533fa5918d |
| institution | Directory Open Access Journal |
| issn | 1516-8484 1806-0870 |
| language | English |
| last_indexed | 2024-12-11T01:02:36Z |
| publishDate | 2011-10-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Revista Brasileira de Hematologia e Hemoterapia |
| spelling | doaj.art-5833adeec3c146af9bbc0e533fa5918d2022-12-22T01:26:16ZengElsevierRevista Brasileira de Hematologia e Hemoterapia1516-84841806-08702011-10-0133538338810.5581/1516-8484.20110103Epstein-Barr virus: general factors, virus-related diseases and measurement of viral load after transplantLuciana Cristina Fagundes GequelinIrina N RiedigerSueli M NakataniAlexander W BiondoCarmem M BonfimThe Epstein-Barr virus is responsible for infectious mononucleosis syndrome and is also closely associated to several types of cancer. The main complication involving Epstein-Barr virus infection, both in recipients of hematopoietic stem cells and solid organs, is post-transplant lymphoproliferative disease. The importance of this disease has increased interest in the development of laboratory tools to improve post-transplant monitoring and to detect the disease before clinical evolution. Viral load analysis for Epstein-Barr virus through real-time polymerase chain reaction is, at present, the best tool to measure viral load. However, there is not a consensus on which sample type is the best for the test and what is its predictive value for therapeutic interventions.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842011000500016Herpesvirus 4, humanPolymerase chain reactionLymphoproliferative disordersTransplantation |
| spellingShingle | Luciana Cristina Fagundes Gequelin Irina N Riediger Sueli M Nakatani Alexander W Biondo Carmem M Bonfim Epstein-Barr virus: general factors, virus-related diseases and measurement of viral load after transplant Revista Brasileira de Hematologia e Hemoterapia Herpesvirus 4, human Polymerase chain reaction Lymphoproliferative disorders Transplantation |
| title | Epstein-Barr virus: general factors, virus-related diseases and measurement of viral load after transplant |
| title_full | Epstein-Barr virus: general factors, virus-related diseases and measurement of viral load after transplant |
| title_fullStr | Epstein-Barr virus: general factors, virus-related diseases and measurement of viral load after transplant |
| title_full_unstemmed | Epstein-Barr virus: general factors, virus-related diseases and measurement of viral load after transplant |
| title_short | Epstein-Barr virus: general factors, virus-related diseases and measurement of viral load after transplant |
| title_sort | epstein barr virus general factors virus related diseases and measurement of viral load after transplant |
| topic | Herpesvirus 4, human Polymerase chain reaction Lymphoproliferative disorders Transplantation |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842011000500016 |
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