Myosin XVI Regulates Actin Cytoskeleton Dynamics in Dendritic Spines of Purkinje Cells and Affects Presynaptic Organization

Myosin XVI Regulates Actin Cytoskeleton Dynamics in Dendritic Spines of Purkinje Cells and Affects Presynaptic Organization

The actin cytoskeleton is crucial for function and morphology of neuronal synapses. Moreover, altered regulation of the neuronal actin cytoskeleton has been implicated in neuropsychiatric diseases such as autism spectrum disorder (ASD). Myosin XVI is a neuronally expressed unconventional myosin know...

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Bibliographic Details
Main Authors: Mona Katrin Roesler, Franco Luis Lombino, Sandra Freitag, Michaela Schweizer, Irm Hermans-Borgmeyer, Jürgen R. Schwarz, Matthias Kneussel, Wolfgang Wagner
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Purkinje cell
dendritic spine
actin cytoskeleton
autism spectrum disorder
Myo16
WAVE
Online Access:https://www.frontiersin.org/article/10.3389/fncel.2019.00330/full

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