Clinical and Laboratory Development of Echinocandin Resistance in Candida glabrata: Molecular Characterization

Clinical and Laboratory Development of Echinocandin Resistance in Candida glabrata: Molecular Characterization

The pathogenic yeast Candida glabrata has become a public health issue due to the increasing number of echinocandin resistant clinical strains reported. In this study, acquisition and development of resistance to this antifungal class were studied in serial C. glabrata isolates from five patients ad...

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Bibliographic Details
Main Authors: Olga Rivero-Menendez, Patricia Navarro-Rodriguez, Leticia Bernal-Martinez, Gema Martin-Cano, Laura Lopez-Perez, Isabel Sanchez-Romero, Ana Perez-Ayala, Javier Capilla, Oscar Zaragoza, Ana Alastruey-Izquierdo
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Microbiology
Subjects:
Candida glabrata
echinocandins
antifungal resistance
FKS
MSH2
genotyping
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01585/full

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