Tissue engineering of human hair follicles using a biomimetic developmental approach

Human skin constructs hold potential for regenerative medicine, but the incorporation of hair follicles into such constructs is a challenge. Here, the authors use 3D printed molds to pattern hair follicle cell types in a physiological organization, and achieve human hair growth on the back of a mous...

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Main Authors: Hasan Erbil Abaci, Abigail Coffman, Yanne Doucet, James Chen, Joanna Jacków, Etienne Wang, Zongyou Guo, Jung U. Shin, Colin A. Jahoda, Angela M. Christiano
Format: Article
Language:English
Published: Nature Portfolio 2018-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-07579-y
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author Hasan Erbil Abaci
Abigail Coffman
Yanne Doucet
James Chen
Joanna Jacków
Etienne Wang
Zongyou Guo
Jung U. Shin
Colin A. Jahoda
Angela M. Christiano
author_facet Hasan Erbil Abaci
Abigail Coffman
Yanne Doucet
James Chen
Joanna Jacków
Etienne Wang
Zongyou Guo
Jung U. Shin
Colin A. Jahoda
Angela M. Christiano
author_sort Hasan Erbil Abaci
collection DOAJ
description Human skin constructs hold potential for regenerative medicine, but the incorporation of hair follicles into such constructs is a challenge. Here, the authors use 3D printed molds to pattern hair follicle cell types in a physiological organization, and achieve human hair growth on the back of a mouse.
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spelling doaj.art-58390131d3fc465c8beb113b90dc07a22022-12-21T21:53:02ZengNature PortfolioNature Communications2041-17232018-12-019111110.1038/s41467-018-07579-yTissue engineering of human hair follicles using a biomimetic developmental approachHasan Erbil Abaci0Abigail Coffman1Yanne Doucet2James Chen3Joanna Jacków4Etienne Wang5Zongyou Guo6Jung U. Shin7Colin A. Jahoda8Angela M. Christiano9Department of Dermatology, Columbia University Medical CenterDepartment of Dermatology, Columbia University Medical CenterDepartment of Dermatology, Columbia University Medical CenterDepartment of Dermatology, Columbia University Medical CenterDepartment of Dermatology, Columbia University Medical CenterDepartment of Dermatology, Columbia University Medical CenterDepartment of Dermatology, Columbia University Medical CenterDepartment of Dermatology, Columbia University Medical CenterDepartment of Biosciences, Durham UniversityDepartment of Dermatology, Columbia University Medical CenterHuman skin constructs hold potential for regenerative medicine, but the incorporation of hair follicles into such constructs is a challenge. Here, the authors use 3D printed molds to pattern hair follicle cell types in a physiological organization, and achieve human hair growth on the back of a mouse.https://doi.org/10.1038/s41467-018-07579-y
spellingShingle Hasan Erbil Abaci
Abigail Coffman
Yanne Doucet
James Chen
Joanna Jacków
Etienne Wang
Zongyou Guo
Jung U. Shin
Colin A. Jahoda
Angela M. Christiano
Tissue engineering of human hair follicles using a biomimetic developmental approach
Nature Communications
title Tissue engineering of human hair follicles using a biomimetic developmental approach
title_full Tissue engineering of human hair follicles using a biomimetic developmental approach
title_fullStr Tissue engineering of human hair follicles using a biomimetic developmental approach
title_full_unstemmed Tissue engineering of human hair follicles using a biomimetic developmental approach
title_short Tissue engineering of human hair follicles using a biomimetic developmental approach
title_sort tissue engineering of human hair follicles using a biomimetic developmental approach
url https://doi.org/10.1038/s41467-018-07579-y
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