EndHiC: assemble large contigs into chromosome-level scaffolds using the Hi-C links from contig ends

EndHiC: assemble large contigs into chromosome-level scaffolds using the Hi-C links from contig ends

Abstract Background The application of PacBio HiFi and ultra-long ONT reads have enabled huge progress in the contig-level assembly, but it is still challenging to assemble large contigs into chromosomes with available Hi-C scaffolding tools, which count Hi-C links between contigs using the whole or...

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Bibliographic Details
Main Authors: Sen Wang, Hengchao Wang, Fan Jiang, Anqi Wang, Hangwei Liu, Hanbo Zhao, Boyuan Yang, Dong Xu, Yan Zhang, Wei Fan
Format: Article
Language:English
Published: BMC 2022-12-01
Series:BMC Bioinformatics
Subjects:
Hi-C
Scaffolding
Contig end
Assembly
Online Access:https://doi.org/10.1186/s12859-022-05087-x

Internet

https://doi.org/10.1186/s12859-022-05087-x

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