High inter-laboratory variability in the assessment of HER2-low breast cancer: a national registry study on 50,714 Danish patients

High inter-laboratory variability in the assessment of HER2-low breast cancer: a national registry study on 50,714 Danish patients

Abstract Background Considering the recent advancements in the treatment of breast cancer with low expression of human epidermal growth factor receptor 2 (HER2), we aimed to examine inter-laboratory variability in the assessment of HER2-low breast cancer across all Danish pathology departments. Meth...

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Bibliographic Details
Main Authors: Kåre Nielsen, Michael Sode, Maj-Britt Jensen, Tobias Berg, Ann Knoop, Bent Ejlertsen, Anne-Vibeke Lænkholm
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Breast Cancer Research
Subjects:
Breast cancer
Human epidermal growth factor receptor 2 (HER2)
HER2 low
Variability
Reproducibility
Immunohistochemistry
Online Access:https://doi.org/10.1186/s13058-023-01739-9

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