<i>Enterococcus hirae</i> Mitral Valve Infectious Endocarditis: A Case Report and Review of the Literature
<i>Enterococcus hirae</i> is a rare pathogen in human infections, although its incidence may be underestimated due to its difficult isolation. We describe the first known case of <i>E. hirae</i> infective endocarditis (IE), which involves the mitral valve alone, and the seven...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-07-01
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| Series: | Antibiotics |
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| Online Access: | https://www.mdpi.com/2079-6382/12/8/1232 |
| _version_ | 1797585749233631232 |
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| author | Roberta Gaudiano Marcello Trizzino Salvatore Torre Roberta Virruso Fabio Fiorino Vincenzo Argano Antonio Cascio |
| author_facet | Roberta Gaudiano Marcello Trizzino Salvatore Torre Roberta Virruso Fabio Fiorino Vincenzo Argano Antonio Cascio |
| author_sort | Roberta Gaudiano |
| collection | DOAJ |
| description | <i>Enterococcus hirae</i> is a rare pathogen in human infections, although its incidence may be underestimated due to its difficult isolation. We describe the first known case of <i>E. hirae</i> infective endocarditis (IE), which involves the mitral valve alone, and the seventh <i>E. hirae</i> IE worldwide. Case presentation: a 62-year-old male was admitted to our department with a five-month history of intermittent fever without responding to antibiotic treatment. His medical history included mitral valve prolapse, recent pleurisy, and lumbar epidural steroid injections due to lumbar degenerative disc disease. Pre-admission transesophageal echocardiography (TEE) showed mitral valve vegetation, and <i>Enterococcus faecium</i> was isolated on blood cultures by MALDI-TOF VITEK MS. During hospitalization, intravenous (IV) therapy with ampicillin and ceftriaxone was initiated, and <i>E. hirae</i> was identified by MALDI-TOF Bruker Biotyper on three blood culture sets. A second TEE revealed mitral valve regurgitation, which worsened due to infection progression. The patient underwent mitral valve replacement with a bioprosthetic valve and had an uncomplicated postoperative course; he was discharged after six weeks of IV ampicillin and ceftriaxone treatment. |
| first_indexed | 2024-03-11T00:11:27Z |
| format | Article |
| id | doaj.art-583f9287f1e24e169f689ae6cd7e6173 |
| institution | Directory Open Access Journal |
| issn | 2079-6382 |
| language | English |
| last_indexed | 2024-03-11T00:11:27Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Antibiotics |
| spelling | doaj.art-583f9287f1e24e169f689ae6cd7e61732023-11-18T23:58:42ZengMDPI AGAntibiotics2079-63822023-07-01128123210.3390/antibiotics12081232<i>Enterococcus hirae</i> Mitral Valve Infectious Endocarditis: A Case Report and Review of the LiteratureRoberta Gaudiano0Marcello Trizzino1Salvatore Torre2Roberta Virruso3Fabio Fiorino4Vincenzo Argano5Antonio Cascio6Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “G D’Alessandro”, University of Palermo, 90127 Palermo, ItalyInfectious and Tropical Disease Unit and Sicilian Regional Reference Center for the Fight against AIDS, AOU Policlinico “P. Giaccone”, 90127 Palermo, ItalyDepartment of Cardiac Surgery, University Hospital “Policlinico”, 90127 Palermo, ItalyUOC of Microbiology, Virology and Parassitology, AOU Policlinico, 90127 Palermo, ItalyDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “G D’Alessandro”, University of Palermo, 90127 Palermo, ItalyDepartment of Cardiac Surgery, University Hospital “Policlinico”, 90127 Palermo, ItalyDepartment of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties “G D’Alessandro”, University of Palermo, 90127 Palermo, Italy<i>Enterococcus hirae</i> is a rare pathogen in human infections, although its incidence may be underestimated due to its difficult isolation. We describe the first known case of <i>E. hirae</i> infective endocarditis (IE), which involves the mitral valve alone, and the seventh <i>E. hirae</i> IE worldwide. Case presentation: a 62-year-old male was admitted to our department with a five-month history of intermittent fever without responding to antibiotic treatment. His medical history included mitral valve prolapse, recent pleurisy, and lumbar epidural steroid injections due to lumbar degenerative disc disease. Pre-admission transesophageal echocardiography (TEE) showed mitral valve vegetation, and <i>Enterococcus faecium</i> was isolated on blood cultures by MALDI-TOF VITEK MS. During hospitalization, intravenous (IV) therapy with ampicillin and ceftriaxone was initiated, and <i>E. hirae</i> was identified by MALDI-TOF Bruker Biotyper on three blood culture sets. A second TEE revealed mitral valve regurgitation, which worsened due to infection progression. The patient underwent mitral valve replacement with a bioprosthetic valve and had an uncomplicated postoperative course; he was discharged after six weeks of IV ampicillin and ceftriaxone treatment.https://www.mdpi.com/2079-6382/12/8/1232<i>Enterococcus hirae</i>infective endocarditismitral valveMALDI-TOF MS |
| spellingShingle | Roberta Gaudiano Marcello Trizzino Salvatore Torre Roberta Virruso Fabio Fiorino Vincenzo Argano Antonio Cascio <i>Enterococcus hirae</i> Mitral Valve Infectious Endocarditis: A Case Report and Review of the Literature Antibiotics <i>Enterococcus hirae</i> infective endocarditis mitral valve MALDI-TOF MS |
| title | <i>Enterococcus hirae</i> Mitral Valve Infectious Endocarditis: A Case Report and Review of the Literature |
| title_full | <i>Enterococcus hirae</i> Mitral Valve Infectious Endocarditis: A Case Report and Review of the Literature |
| title_fullStr | <i>Enterococcus hirae</i> Mitral Valve Infectious Endocarditis: A Case Report and Review of the Literature |
| title_full_unstemmed | <i>Enterococcus hirae</i> Mitral Valve Infectious Endocarditis: A Case Report and Review of the Literature |
| title_short | <i>Enterococcus hirae</i> Mitral Valve Infectious Endocarditis: A Case Report and Review of the Literature |
| title_sort | i enterococcus hirae i mitral valve infectious endocarditis a case report and review of the literature |
| topic | <i>Enterococcus hirae</i> infective endocarditis mitral valve MALDI-TOF MS |
| url | https://www.mdpi.com/2079-6382/12/8/1232 |
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