Another wrinkle with age: Aged collagen and intra‐peritoneal metastasis of ovarian cancer

Another wrinkle with age: Aged collagen and intra‐peritoneal metastasis of ovarian cancer

Abstract Background Age is the most significant risk factor for ovarian cancer (OvCa), the deadliest gynecologic malignancy. Metastasizing OvCa cells adhere to the omentum, a peritoneal structure rich in collagen, adipocytes, and immune cells. Ultrastructural changes in the omentum and the omental c...

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Bibliographic Details
Main Authors: Elizabeth I. Harper, Tyvette S. Hilliard, Emma F. Sheedy, Preston Carey, Paul Wilkinson, Michael D. Siroky, Jing Yang, Elizabeth Agadi, Annemarie K. Leonard, Ethan Low, Yueying Liu, Arya Biragyn, Christina M. Annunziata, Mary Sharon Stack
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:Aging and Cancer
Subjects:
aging
collagen
metastasis
omentum
ovarian cancer
Online Access:https://doi.org/10.1002/aac2.12049

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