Effects of substrate binding site residue substitutions of xynA from Bacillus amyloliquefaciens on substrate specificity

Effects of substrate binding site residue substitutions of xynA from Bacillus amyloliquefaciens on substrate specificity

Abstract Background The aromatic residues of xylanase enzyme, W187, Y124, W144, Y128 and W63 of substrate binding pocket from Bacillus amyloliquefaciens were investigated for their role in substrate binding by homology modelling and sequence analysis. These residues are highly conserved and play an...

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Bibliographic Details
Main Authors: Anil S. Prajapati, Vishakha A. Pawar, Ketankumar J. Panchal, Ankit P. Sudhir, Bhaumik R. Dave, Darshan H. Patel, R. B. Subramanian
Format: Article
Language:English
Published: BMC 2018-02-01
Series:BMC Biotechnology
Subjects:
Xylanase
Site-directed mutagenesis
Protein engineering
Substrate specificity
Online Access:http://link.springer.com/article/10.1186/s12896-018-0420-7

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