Inferring joint sequence-structural determinants of protein functional specificity
Residues responsible for allostery, cooperativity, and other subtle but functionally important interactions remain difficult to detect. To aid such detection, we employ statistical inference based on the assumption that residues distinguishing a protein subgroup from evolutionarily divergent subgrou...
Main Authors: | Andrew F Neuwald, L Aravind, Stephen F Altschul |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2018-01-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/29880 |
Similar Items
-
SPARC: Structural properties associated with residue constraints
by: Andrew F. Neuwald, et al.
Published: (2022-01-01) -
Spatial cluster modelling /
by: Lawson, Andrew (Andrew B.), et al.
Published: (2002) -
Statistical data preprocessing methods in distance functions to enhance k-means clustering algorithm
by: Dalatu, Paul Inuwa
Published: (2018) -
Literature review : cluster analysis /
by: 494692 Robiah Adnan
Published: (1995) -
Infer HIV transmission dynamics from gene sequences among young men who have sex with men in China
by: Xin Jin, et al.
Published: (2021-01-01)