Morphological features predicting in-stent stenosis after pipeline implantation for unruptured intracranial aneurysm
PurposeElongation denotes the regularity of an aneurysm and parent artery. This retrospective research study was conducted to identify the morphological factors that could predict postoperative in-stent stenosis (ISS) after Pipeline Embolization Device (PED) implantation for unruptured intracranial...
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| Format: | Article |
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Frontiers Media S.A.
2023-05-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fneur.2023.1121134/full |
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| author | Hengwei Jin Hengwei Jin Jian Lv Jian Lv Conghui Li Jiwei Wang Yuhua Jiang Yuhua Jiang Xiangyu Meng Youxiang Li Youxiang Li |
| author_facet | Hengwei Jin Hengwei Jin Jian Lv Jian Lv Conghui Li Jiwei Wang Yuhua Jiang Yuhua Jiang Xiangyu Meng Youxiang Li Youxiang Li |
| author_sort | Hengwei Jin |
| collection | DOAJ |
| description | PurposeElongation denotes the regularity of an aneurysm and parent artery. This retrospective research study was conducted to identify the morphological factors that could predict postoperative in-stent stenosis (ISS) after Pipeline Embolization Device (PED) implantation for unruptured intracranial aneurysms (UIAs).MethodsPatients with UIA and treated with PED at our institute between 2015 and 2020 were selected. Preoperative morphological features including both manually measured shape features and radiomics shape features were extracted and compared between patients with and without ISS. Logistic regression analysis was performed for factors associated with postoperative ISS.ResultsA total of 52 patients (18 men and 34 women) were involved in this study. The mean angiographic follow-up time was 11.87 ± 8.26 months. Of the patients, 20 of them (38.46%) were identified with ISS. Multivariate logistic analysis showed that elongation (odds ratio = 0.008; 95% confidence interval, 0.001–0.255; p = 0.006) was an independent risk factor for ISS. The area under the curve (AUC) of the receiver operating characteristic curve(ROC) was 0.734 and the optimal cut-off value of elongation for ISS classification was 0.595. The sensitivity and specificity of prediction were 0.6 and 0.781, respectively. The ISS degree of elongation of less than 0.595 was larger than the ISS degree of elongation of more than 0.595.ConclusionElongation is a potential risk factor associated with ISS after PED implantation for UIAs. The more regular an aneurysm and parent artery, the less likelihood of an ISS occurrence. |
| first_indexed | 2024-04-09T13:14:31Z |
| format | Article |
| id | doaj.art-5847f8c93eea4271971a7447ec65f5f9 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-04-09T13:14:31Z |
| publishDate | 2023-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-5847f8c93eea4271971a7447ec65f5f92023-05-12T04:43:20ZengFrontiers Media S.A.Frontiers in Neurology1664-22952023-05-011410.3389/fneur.2023.11211341121134Morphological features predicting in-stent stenosis after pipeline implantation for unruptured intracranial aneurysmHengwei Jin0Hengwei Jin1Jian Lv2Jian Lv3Conghui Li4Jiwei Wang5Yuhua Jiang6Yuhua Jiang7Xiangyu Meng8Youxiang Li9Youxiang Li10Department of Neurosurgery, Beijing Tiantan Hospital and Beijing Neurosurgical Institute, Capital Medical University, Beijing, ChinaDepartment of Neurointerventional Engineering and Technology, Beijing Engineering Research Center, Beijing, ChinaDepartment of Neurointerventional Engineering and Technology, Beijing Engineering Research Center, Beijing, ChinaDepartment of Neurosurgery, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital Medical University, Beijing, ChinaDepartment of Neurosurgery, The First Hospital, Hebei Medical University, Shijiazhuang, ChinaDepartment of Neurosurgery, The First Hospital, Hebei Medical University, Shijiazhuang, ChinaDepartment of Neurointerventional Engineering and Technology, Beijing Engineering Research Center, Beijing, ChinaDepartment of Neurosurgery, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital Medical University, Beijing, ChinaDepartment of Neurosurgery, The First Hospital, Hebei Medical University, Shijiazhuang, ChinaDepartment of Neurointerventional Engineering and Technology, Beijing Engineering Research Center, Beijing, ChinaDepartment of Neurosurgery, Beijing Neurosurgical Institute and Beijing Tiantan Hospital, Capital Medical University, Beijing, ChinaPurposeElongation denotes the regularity of an aneurysm and parent artery. This retrospective research study was conducted to identify the morphological factors that could predict postoperative in-stent stenosis (ISS) after Pipeline Embolization Device (PED) implantation for unruptured intracranial aneurysms (UIAs).MethodsPatients with UIA and treated with PED at our institute between 2015 and 2020 were selected. Preoperative morphological features including both manually measured shape features and radiomics shape features were extracted and compared between patients with and without ISS. Logistic regression analysis was performed for factors associated with postoperative ISS.ResultsA total of 52 patients (18 men and 34 women) were involved in this study. The mean angiographic follow-up time was 11.87 ± 8.26 months. Of the patients, 20 of them (38.46%) were identified with ISS. Multivariate logistic analysis showed that elongation (odds ratio = 0.008; 95% confidence interval, 0.001–0.255; p = 0.006) was an independent risk factor for ISS. The area under the curve (AUC) of the receiver operating characteristic curve(ROC) was 0.734 and the optimal cut-off value of elongation for ISS classification was 0.595. The sensitivity and specificity of prediction were 0.6 and 0.781, respectively. The ISS degree of elongation of less than 0.595 was larger than the ISS degree of elongation of more than 0.595.ConclusionElongation is a potential risk factor associated with ISS after PED implantation for UIAs. The more regular an aneurysm and parent artery, the less likelihood of an ISS occurrence.https://www.frontiersin.org/articles/10.3389/fneur.2023.1121134/fullin-stent stenosis (ISS)pipelineradiomicsunruptured intracranial aneurysm (UIA)morphology |
| spellingShingle | Hengwei Jin Hengwei Jin Jian Lv Jian Lv Conghui Li Jiwei Wang Yuhua Jiang Yuhua Jiang Xiangyu Meng Youxiang Li Youxiang Li Morphological features predicting in-stent stenosis after pipeline implantation for unruptured intracranial aneurysm Frontiers in Neurology in-stent stenosis (ISS) pipeline radiomics unruptured intracranial aneurysm (UIA) morphology |
| title | Morphological features predicting in-stent stenosis after pipeline implantation for unruptured intracranial aneurysm |
| title_full | Morphological features predicting in-stent stenosis after pipeline implantation for unruptured intracranial aneurysm |
| title_fullStr | Morphological features predicting in-stent stenosis after pipeline implantation for unruptured intracranial aneurysm |
| title_full_unstemmed | Morphological features predicting in-stent stenosis after pipeline implantation for unruptured intracranial aneurysm |
| title_short | Morphological features predicting in-stent stenosis after pipeline implantation for unruptured intracranial aneurysm |
| title_sort | morphological features predicting in stent stenosis after pipeline implantation for unruptured intracranial aneurysm |
| topic | in-stent stenosis (ISS) pipeline radiomics unruptured intracranial aneurysm (UIA) morphology |
| url | https://www.frontiersin.org/articles/10.3389/fneur.2023.1121134/full |
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