Generation of Fel d 1 chain 2 genome-edited cats by CRISPR-Cas9 system

Generation of Fel d 1 chain 2 genome-edited cats by CRISPR-Cas9 system

Abstract Allergens from domestic cats (Felis catus) cause allergy-related health problems worldwide. Fel d 1 is a major allergen that causes severe allergic reactions in humans, including rhinitis, conjunctivitis, and life-threatening asthma. Therefore, patients with cat allergies anticipate hypoall...

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Bibliographic Details
Main Authors: Sang Ryeul Lee, Kyung-Lim Lee, Seok-Hwan Song, Myeong-Don Joo, Seo-Hyun Lee, Ji-Su Kang, Seon-Min Kang, Muhammad Idrees, Jae-Wook Kim, Il-Keun Kong
Format: Article
Language:English
Published: Nature Portfolio 2024-02-01
Series:Scientific Reports
Subjects:
Allergen
Fel d 1
CH2
Genome-edited cats
CRISPR-Cas9
Hypoallergenic cats
Online Access:https://doi.org/10.1038/s41598-024-55464-0

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