Risk Factors for Stroke-associated Pneumonia: A Prospective Cohort Study
<strong>Background:</strong> stroke-associated pneumonia prolongs hospital stay and is an important risk factor for morbidity and mortality. <br /><strong>Objective:</strong> to determine risk factors for stroke-associated pneumonia. <strong><br />Methods:&l...
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| Format: | Article |
| Language: | Spanish |
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Universidad de las Ciencias Médicas de Cienfuegos
2015-12-01
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| Series: | Revista Finlay |
| Subjects: | |
| Online Access: | https://revfinlay.sld.cu/index.php/finlay/article/view/376 |
| _version_ | 1797301788785770496 |
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| author | Alexis Suárez Quesada Ezequiel López Espinosa Noelsis García Verdecia Miguel Ángel Serra Valdés |
| author_facet | Alexis Suárez Quesada Ezequiel López Espinosa Noelsis García Verdecia Miguel Ángel Serra Valdés |
| author_sort | Alexis Suárez Quesada |
| collection | DOAJ |
| description | <strong>Background:</strong> stroke-associated pneumonia prolongs hospital stay and is an important risk factor for morbidity and mortality. <br /><strong>Objective:</strong> to determine risk factors for stroke-associated pneumonia. <strong><br />Methods:</strong> a prospective single-cohort study was conducted involving 390 patients aged 16-93 years who met clinical and neuroimaging criteria for acute stroke treated at the Carlos Manuel de Céspedes Hospital from January 2012 through March 2015. Univariate comparison of qualitative variables was performed by using the Kaplan-Meier method. The Cox regression model was applied for multivariate analysis of risk factors for pneumonia. The area under the ROC curve was used to determine the discriminatory power of the model. <strong><br />Results:</strong> two hundred thirteen patients (54.6 %) with ischemic stroke and 177 (45.4 %) with hemorrhagic stroke were studied. Cases of nosocomial pneumonia after acute stroke accounted for 25.4 %. Subjects who developed pneumonia had lower scores on the Glasgow scale and higher scores on the modified Rankin scale. The following risk factors were identified using the Cox regression model: Glasgow coma score (Exp (B): 0.687; 95 % CI 0.630 to 0.750) and stroke subtype (Exp (B): 1.723; 95 % CI 1.137 to 2.610). The area under the ROC curve was 0.88.<br /> <strong>Conclusions:</strong> the risk factors for the development of nosocomial pneumonia after acute stroke found were the level of consciousness and suffering a hemorrhagic stroke. Other influencing variables are chronic obstructive pulmonary disease and heart disease as a comorbid condition. |
| first_indexed | 2024-03-07T23:27:44Z |
| format | Article |
| id | doaj.art-584af8927f594874872a94175ebf0c83 |
| institution | Directory Open Access Journal |
| issn | 2221-2434 |
| language | Spanish |
| last_indexed | 2024-03-07T23:27:44Z |
| publishDate | 2015-12-01 |
| publisher | Universidad de las Ciencias Médicas de Cienfuegos |
| record_format | Article |
| series | Revista Finlay |
| spelling | doaj.art-584af8927f594874872a94175ebf0c832024-02-21T02:59:17ZspaUniversidad de las Ciencias Médicas de CienfuegosRevista Finlay2221-24342015-12-0154242252236Risk Factors for Stroke-associated Pneumonia: A Prospective Cohort StudyAlexis Suárez Quesada0Ezequiel López Espinosa1Noelsis García Verdecia2Miguel Ángel Serra Valdés3Hospital General Universitario Carlos Manuel de Céspedes. Granma.Hospital General Universitario Carlos Manuel de Céspedes. Granma.Hospital General Universitario Carlos Manuel de Céspedes. Granma.Hospital General Docente Enrique Cabrera. La Habana.<strong>Background:</strong> stroke-associated pneumonia prolongs hospital stay and is an important risk factor for morbidity and mortality. <br /><strong>Objective:</strong> to determine risk factors for stroke-associated pneumonia. <strong><br />Methods:</strong> a prospective single-cohort study was conducted involving 390 patients aged 16-93 years who met clinical and neuroimaging criteria for acute stroke treated at the Carlos Manuel de Céspedes Hospital from January 2012 through March 2015. Univariate comparison of qualitative variables was performed by using the Kaplan-Meier method. The Cox regression model was applied for multivariate analysis of risk factors for pneumonia. The area under the ROC curve was used to determine the discriminatory power of the model. <strong><br />Results:</strong> two hundred thirteen patients (54.6 %) with ischemic stroke and 177 (45.4 %) with hemorrhagic stroke were studied. Cases of nosocomial pneumonia after acute stroke accounted for 25.4 %. Subjects who developed pneumonia had lower scores on the Glasgow scale and higher scores on the modified Rankin scale. The following risk factors were identified using the Cox regression model: Glasgow coma score (Exp (B): 0.687; 95 % CI 0.630 to 0.750) and stroke subtype (Exp (B): 1.723; 95 % CI 1.137 to 2.610). The area under the ROC curve was 0.88.<br /> <strong>Conclusions:</strong> the risk factors for the development of nosocomial pneumonia after acute stroke found were the level of consciousness and suffering a hemorrhagic stroke. Other influencing variables are chronic obstructive pulmonary disease and heart disease as a comorbid condition.https://revfinlay.sld.cu/index.php/finlay/article/view/376accidente cerebrovascularneumoníainfección hospitalariafactores de riesgomortalidadmorbilidad |
| spellingShingle | Alexis Suárez Quesada Ezequiel López Espinosa Noelsis García Verdecia Miguel Ángel Serra Valdés Risk Factors for Stroke-associated Pneumonia: A Prospective Cohort Study Revista Finlay accidente cerebrovascular neumonía infección hospitalaria factores de riesgo mortalidad morbilidad |
| title | Risk Factors for Stroke-associated Pneumonia: A Prospective Cohort Study |
| title_full | Risk Factors for Stroke-associated Pneumonia: A Prospective Cohort Study |
| title_fullStr | Risk Factors for Stroke-associated Pneumonia: A Prospective Cohort Study |
| title_full_unstemmed | Risk Factors for Stroke-associated Pneumonia: A Prospective Cohort Study |
| title_short | Risk Factors for Stroke-associated Pneumonia: A Prospective Cohort Study |
| title_sort | risk factors for stroke associated pneumonia a prospective cohort study |
| topic | accidente cerebrovascular neumonía infección hospitalaria factores de riesgo mortalidad morbilidad |
| url | https://revfinlay.sld.cu/index.php/finlay/article/view/376 |
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