Treatment of Retinal Separation in HIV-infected Patients with Cytomegalovirus Retinitis
HIV infection — is a socially significant problem for many countries, as the infected die in an average of 10-11 years due to the immunodeficiency virus. Up to 20% of patients with AIDS lose their sight because of cytomegalovirus retinitis (CMV retinitis), which occurs in 70% of HIV-infected people....
| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
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Ophthalmology Publishing Group
2017-03-01
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| Series: | Oftalʹmologiâ |
| Subjects: | |
| Online Access: | https://www.ophthalmojournal.com/opht/article/view/358 |
| _version_ | 1797875515794653184 |
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| author | A. L. Onischenko A. V. Kolbasko G. N. Tatarnikova A. D. Chernysheva |
| author_facet | A. L. Onischenko A. V. Kolbasko G. N. Tatarnikova A. D. Chernysheva |
| author_sort | A. L. Onischenko |
| collection | DOAJ |
| description | HIV infection — is a socially significant problem for many countries, as the infected die in an average of 10-11 years due to the immunodeficiency virus. Up to 20% of patients with AIDS lose their sight because of cytomegalovirus retinitis (CMV retinitis), which occurs in 70% of HIV-infected people. In some patients with HIV infection blindness occurs because of acute retinal necrosis of CMV etiology. The algorithm of CMV retinitis treatment in HIV-infected patients is described in modern manuals (ganciclovir, valganciclovir, foscarnet and others on the background of antiretroviral therapy), but the tactics of treatment of retinal separation in these patients is not clearly defined. It may be “wait and see”, providing conservative treatment with antiviral drugs, and the active tactics — vitreoretinal surgery. In this article the authors present their personal clinical observations of three HIV-infected patients with CMV retinitis at the age of 8 to 36 years with a detailed analysis of the clinical data and the results of the laboratory tests. In particular, the authors give their own results of intravitreal introduction of ganciclovir in patients with CMV retinitis. Given the poor prognosis for the life of these patients, the authors put a deontological question of justification of active treatment of retinal separation in AIDS patients with CMV retinitis. |
| first_indexed | 2024-04-10T01:47:42Z |
| format | Article |
| id | doaj.art-58553b3f31354241a65f200badfcad6e |
| institution | Directory Open Access Journal |
| issn | 1816-5095 2500-0845 |
| language | Russian |
| last_indexed | 2024-04-10T01:47:42Z |
| publishDate | 2017-03-01 |
| publisher | Ophthalmology Publishing Group |
| record_format | Article |
| series | Oftalʹmologiâ |
| spelling | doaj.art-58553b3f31354241a65f200badfcad6e2023-03-13T09:08:37ZrusOphthalmology Publishing GroupOftalʹmologiâ1816-50952500-08452017-03-01141848710.18008/1816-5095-2017-1-84-87330Treatment of Retinal Separation in HIV-infected Patients with Cytomegalovirus RetinitisA. L. Onischenko0A. V. Kolbasko1G. N. Tatarnikova2A. D. Chernysheva3Государственное бюджетное образовательное учреждение дополнительного профессионального образования «Новокузнецкий ГИУВ» Министерства здравоохранения Российской ФедерацииГосударственное бюджетное образовательное учреждение дополнительного профессионального образования «Новокузнецкий ГИУВ» Министерства здравоохранения Российской ФедерацииГосударственное бюджетное образовательное учреждение дополнительного профессионального образования «Новокузнецкий ГИУВ» Министерства здравоохранения Российской ФедерацииГосударственное бюджетное образовательное учреждение дополнительного профессионального образования «Новокузнецкий ГИУВ» Министерства здравоохранения Российской ФедерацииHIV infection — is a socially significant problem for many countries, as the infected die in an average of 10-11 years due to the immunodeficiency virus. Up to 20% of patients with AIDS lose their sight because of cytomegalovirus retinitis (CMV retinitis), which occurs in 70% of HIV-infected people. In some patients with HIV infection blindness occurs because of acute retinal necrosis of CMV etiology. The algorithm of CMV retinitis treatment in HIV-infected patients is described in modern manuals (ganciclovir, valganciclovir, foscarnet and others on the background of antiretroviral therapy), but the tactics of treatment of retinal separation in these patients is not clearly defined. It may be “wait and see”, providing conservative treatment with antiviral drugs, and the active tactics — vitreoretinal surgery. In this article the authors present their personal clinical observations of three HIV-infected patients with CMV retinitis at the age of 8 to 36 years with a detailed analysis of the clinical data and the results of the laboratory tests. In particular, the authors give their own results of intravitreal introduction of ganciclovir in patients with CMV retinitis. Given the poor prognosis for the life of these patients, the authors put a deontological question of justification of active treatment of retinal separation in AIDS patients with CMV retinitis.https://www.ophthalmojournal.com/opht/article/view/358спидцитомегаловирусный ретинитотслойка сетчаткиганцикловир |
| spellingShingle | A. L. Onischenko A. V. Kolbasko G. N. Tatarnikova A. D. Chernysheva Treatment of Retinal Separation in HIV-infected Patients with Cytomegalovirus Retinitis Oftalʹmologiâ спид цитомегаловирусный ретинит отслойка сетчатки ганцикловир |
| title | Treatment of Retinal Separation in HIV-infected Patients with Cytomegalovirus Retinitis |
| title_full | Treatment of Retinal Separation in HIV-infected Patients with Cytomegalovirus Retinitis |
| title_fullStr | Treatment of Retinal Separation in HIV-infected Patients with Cytomegalovirus Retinitis |
| title_full_unstemmed | Treatment of Retinal Separation in HIV-infected Patients with Cytomegalovirus Retinitis |
| title_short | Treatment of Retinal Separation in HIV-infected Patients with Cytomegalovirus Retinitis |
| title_sort | treatment of retinal separation in hiv infected patients with cytomegalovirus retinitis |
| topic | спид цитомегаловирусный ретинит отслойка сетчатки ганцикловир |
| url | https://www.ophthalmojournal.com/opht/article/view/358 |
| work_keys_str_mv | AT alonischenko treatmentofretinalseparationinhivinfectedpatientswithcytomegalovirusretinitis AT avkolbasko treatmentofretinalseparationinhivinfectedpatientswithcytomegalovirusretinitis AT gntatarnikova treatmentofretinalseparationinhivinfectedpatientswithcytomegalovirusretinitis AT adchernysheva treatmentofretinalseparationinhivinfectedpatientswithcytomegalovirusretinitis |