A high-throughput LC-MS/MS method for the measurement of the bile acid/salt content in microbiome-derived sample sets

A high-throughput LC-MS/MS method for the measurement of the bile acid/salt content in microbiome-derived sample sets

Due to the physicochemical properties of bile acids/salts (i.e., hydrophobic and ionizable), the application of reverse-phase liquid chromatography-tandem mass spectrometry (LC-MS/MS)-based methods are ideally suited for the measurement of these compounds in a host of microbiologically-relevant matr...

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Bibliographic Details
Main Authors: Thomas D. Horvath, Sigmund J. Haidacher, Kathleen M. Hoch, Jennifer M. Auchtung, Anthony M. Haag
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:MethodsX
Subjects:
Bioanalytical chemistry
High-throughput sample analysis
High-performance liquid chromatography
LC-MS/MS
Microbiome
Microbiology
Online Access:http://www.sciencedirect.com/science/article/pii/S2215016120301710

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