Evaluation of immune response after moderate and overtraining exercise in wistar rat
Objective(s): The effect of prolonged overtraining on cytokine kinetics was compared with moderate exercise in the present study. Materials and Methods: Male Wistar rats were randomly divided into control sedentary (C), moderate trained (MT), (V=20 m/min, 30 min/day for 6 days a week, 8 weeks),...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Mashhad University of Medical Sciences
2014-01-01
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| Series: | Iranian Journal of Basic Medical Sciences |
| Subjects: | |
| Online Access: | http://ijbms.mums.ac.ir/pdf_2148_9ff0a6a6b98ee77c5507864de248c221.html |
| _version_ | 1818824250298990592 |
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| author | Zahra Gholamnezhad Mohammad Hossein Boskabady Mahmoud Hossein Mojtaba Sankian Abolfazl Khajavi Rad |
| author_facet | Zahra Gholamnezhad Mohammad Hossein Boskabady Mahmoud Hossein Mojtaba Sankian Abolfazl Khajavi Rad |
| author_sort | Zahra Gholamnezhad |
| collection | DOAJ |
| description | Objective(s):
The effect of prolonged overtraining on cytokine kinetics was compared with moderate exercise in the present study.
Materials and Methods:
Male Wistar rats were randomly divided into control sedentary (C), moderate trained (MT), (V=20 m/min, 30 min/day for 6 days a week, 8 weeks), overtrained (OT) (V=25 m/min, 60min/day for 6 days a week, 11 weeks) and recovered overtrained (OR) (OT plus 2 weeks recovery) groups, (n=6 for each group). Immediately, 24 hr and 2 weeks (in OR) after last bout of exercise blood samples were obtained. The plasma concentrations of TNFα, IL-6, IL-10, IL-4 and IFN were measured by ELISA method.
Results:
Immediately after last bout of exercise the following findings were observed; IL-6, IL-10 and TNFαconcentrations increased in OT and OR groups compared with control (P |
| first_indexed | 2024-12-18T23:52:53Z |
| format | Article |
| id | doaj.art-585747d0c21149a0aba464efc5e80c01 |
| institution | Directory Open Access Journal |
| issn | 2008-3866 2008-3874 |
| language | English |
| last_indexed | 2024-12-18T23:52:53Z |
| publishDate | 2014-01-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Basic Medical Sciences |
| spelling | doaj.art-585747d0c21149a0aba464efc5e80c012022-12-21T20:46:51ZengMashhad University of Medical SciencesIranian Journal of Basic Medical Sciences2008-38662008-38742014-01-01171182148Evaluation of immune response after moderate and overtraining exercise in wistar ratZahra Gholamnezhad0Mohammad Hossein Boskabady1Mahmoud Hossein2Mojtaba Sankian3Abolfazl Khajavi Rad4Neurogenic Inflammation Research Centre and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IranNeurogenic Inflammation Research Centre and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IranNeurocognitive Research Centre, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IranImmunology Research Center, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IranNeurogenic Inflammation Research Centre and Department of Physiology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, IranObjective(s): The effect of prolonged overtraining on cytokine kinetics was compared with moderate exercise in the present study. Materials and Methods: Male Wistar rats were randomly divided into control sedentary (C), moderate trained (MT), (V=20 m/min, 30 min/day for 6 days a week, 8 weeks), overtrained (OT) (V=25 m/min, 60min/day for 6 days a week, 11 weeks) and recovered overtrained (OR) (OT plus 2 weeks recovery) groups, (n=6 for each group). Immediately, 24 hr and 2 weeks (in OR) after last bout of exercise blood samples were obtained. The plasma concentrations of TNFα, IL-6, IL-10, IL-4 and IFN were measured by ELISA method. Results: Immediately after last bout of exercise the following findings were observed; IL-6, IL-10 and TNFαconcentrations increased in OT and OR groups compared with control (Phttp://ijbms.mums.ac.ir/pdf_2148_9ff0a6a6b98ee77c5507864de248c221.htmlImmune system Moderate exercise Overtraining exercise Rat Th1 Th2 |
| spellingShingle | Zahra Gholamnezhad Mohammad Hossein Boskabady Mahmoud Hossein Mojtaba Sankian Abolfazl Khajavi Rad Evaluation of immune response after moderate and overtraining exercise in wistar rat Iranian Journal of Basic Medical Sciences Immune system Moderate exercise Overtraining exercise Rat Th1 Th2 |
| title | Evaluation of immune response after moderate and overtraining exercise in wistar rat |
| title_full | Evaluation of immune response after moderate and overtraining exercise in wistar rat |
| title_fullStr | Evaluation of immune response after moderate and overtraining exercise in wistar rat |
| title_full_unstemmed | Evaluation of immune response after moderate and overtraining exercise in wistar rat |
| title_short | Evaluation of immune response after moderate and overtraining exercise in wistar rat |
| title_sort | evaluation of immune response after moderate and overtraining exercise in wistar rat |
| topic | Immune system Moderate exercise Overtraining exercise Rat Th1 Th2 |
| url | http://ijbms.mums.ac.ir/pdf_2148_9ff0a6a6b98ee77c5507864de248c221.html |
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