Correlation between polymorphisms in toll-like receptor genes and the activity of hepatitis B virus among treatment-naïve patients: a case-control study in a Han Chinese population

Correlation between polymorphisms in toll-like receptor genes and the activity of hepatitis B virus among treatment-naïve patients: a case-control study in a Han Chinese population

Abstract Background Because of the high prevalence and absence of cure for infection, chronic hepatitis B virus (HBV) infection has been acknowledged as a pressing public health issue. Toll-like receptors (TLRs) activate the human innate immune system and the polymorphisms in TLRs may alter their fu...

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Bibliographic Details
Main Authors: Yong Lin, Zheng-Xiang Gao, Xu Shen, Mei-Jun Chen, Yan-Ting Li, Shu-Lian Li, Hui-Ling Lin, Qi-Feng Zhao, Fan Liu, Jian-Jun Niu
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Infectious Diseases
Subjects:
Toll-like receptors
Hepatitis activity
Immune response
Hepatitis B virus
Online Access:http://link.springer.com/article/10.1186/s12879-018-2943-x

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