A Key Molecular Regulator, RNA G-Quadruplex and Its Function in Plants
RNA structure plays key roles in plant growth, development, and adaptation. One of the complex RNA structures is the RNA G-quadruplex (RG4) where guanine-rich sequences are folded into two or more layers of G-quartets. Previous computational predictions of RG4 revealed that it is widespread across t...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-06-01
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| Series: | Frontiers in Plant Science |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fpls.2022.926953/full |
| _version_ | 1811243376170762240 |
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| author | Haifeng Liu Haifeng Liu Zhaohui Chu Xiaofei Yang Xiaofei Yang Xiaofei Yang |
| author_facet | Haifeng Liu Haifeng Liu Zhaohui Chu Xiaofei Yang Xiaofei Yang Xiaofei Yang |
| author_sort | Haifeng Liu |
| collection | DOAJ |
| description | RNA structure plays key roles in plant growth, development, and adaptation. One of the complex RNA structures is the RNA G-quadruplex (RG4) where guanine-rich sequences are folded into two or more layers of G-quartets. Previous computational predictions of RG4 revealed that it is widespread across the whole transcriptomes in many plant species, raising the hypothesis that RG4 is likely to be an important regulatory motif in plants. Recently, with the advances in both high-throughput sequencing and cell imaging technologies, RG4 can be detected in living cells as well as at the genome-wide scale. Here, we provide a comprehensive review of recent developments in new methods for detecting RG4 in plants. We also summarize the new functions of RG4 in regulating plant growth and development. We then discuss the possible role of RG4 in adapting to environmental conditions along with evolutionary perspectives. |
| first_indexed | 2024-04-12T14:06:21Z |
| format | Article |
| id | doaj.art-585c0837869b4912adfdc93945cabb9f |
| institution | Directory Open Access Journal |
| issn | 1664-462X |
| language | English |
| last_indexed | 2024-04-12T14:06:21Z |
| publishDate | 2022-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Plant Science |
| spelling | doaj.art-585c0837869b4912adfdc93945cabb9f2022-12-22T03:30:03ZengFrontiers Media S.A.Frontiers in Plant Science1664-462X2022-06-011310.3389/fpls.2022.926953926953A Key Molecular Regulator, RNA G-Quadruplex and Its Function in PlantsHaifeng Liu0Haifeng Liu1Zhaohui Chu2Xiaofei Yang3Xiaofei Yang4Xiaofei Yang5State Key Laboratory of Crop Biology, College of Agronomy, Shandong Agricultural University, Taian, ChinaDepartment of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich, United KingdomState Key Laboratory of Hybrid Rice, Hubei Hongshan Laboratory, College of Life Sciences, Wuhan University, Wuhan, ChinaDepartment of Cell and Developmental Biology, John Innes Centre, Norwich Research Park, Norwich, United KingdomNational Key Laboratory of Plant Molecular Genetics, CAS Centre for Excellence in Molecular Plant Sciences, Shanghai, ChinaCAS-JIC Centre of Excellence for Plant and Microbial Science, Shanghai, ChinaRNA structure plays key roles in plant growth, development, and adaptation. One of the complex RNA structures is the RNA G-quadruplex (RG4) where guanine-rich sequences are folded into two or more layers of G-quartets. Previous computational predictions of RG4 revealed that it is widespread across the whole transcriptomes in many plant species, raising the hypothesis that RG4 is likely to be an important regulatory motif in plants. Recently, with the advances in both high-throughput sequencing and cell imaging technologies, RG4 can be detected in living cells as well as at the genome-wide scale. Here, we provide a comprehensive review of recent developments in new methods for detecting RG4 in plants. We also summarize the new functions of RG4 in regulating plant growth and development. We then discuss the possible role of RG4 in adapting to environmental conditions along with evolutionary perspectives.https://www.frontiersin.org/articles/10.3389/fpls.2022.926953/fullRNA structureRNA G-quadruplex structuregene expressionplant growth and developmentevolution |
| spellingShingle | Haifeng Liu Haifeng Liu Zhaohui Chu Xiaofei Yang Xiaofei Yang Xiaofei Yang A Key Molecular Regulator, RNA G-Quadruplex and Its Function in Plants Frontiers in Plant Science RNA structure RNA G-quadruplex structure gene expression plant growth and development evolution |
| title | A Key Molecular Regulator, RNA G-Quadruplex and Its Function in Plants |
| title_full | A Key Molecular Regulator, RNA G-Quadruplex and Its Function in Plants |
| title_fullStr | A Key Molecular Regulator, RNA G-Quadruplex and Its Function in Plants |
| title_full_unstemmed | A Key Molecular Regulator, RNA G-Quadruplex and Its Function in Plants |
| title_short | A Key Molecular Regulator, RNA G-Quadruplex and Its Function in Plants |
| title_sort | key molecular regulator rna g quadruplex and its function in plants |
| topic | RNA structure RNA G-quadruplex structure gene expression plant growth and development evolution |
| url | https://www.frontiersin.org/articles/10.3389/fpls.2022.926953/full |
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