Importance of the association of molecular and immunological diagnosis in immunocompetent patient with Histoplasma capsulatum and Cryptoccocus neoformans infection: a case report
This case reports an immunocompetent 29-year-old woman with suspected pneumonia, suggestive of fungal infection. Immunoblotting analysis reactivity againstHistoplasma capsulatum and Paracoccidioides brasiliensis were observed. Nested-PCR in blood employing species-specific primers was positive for H...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
SciELO
2014-10-01
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| Series: | Journal of Venomous Animals and Toxins including Tropical Diseases |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200507&lng=en&tlng=en |
| _version_ | 1811324430172815360 |
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| author | Kátia Cristina Dantas Roseli Santos de Freitas Roberta Scholz Pinto Garcia Marcos Vinícius da Silva Edna Cleide Mendes Muricy Valdelene Sayuri Kohara Adriana Pardini Vicentini |
| author_facet | Kátia Cristina Dantas Roseli Santos de Freitas Roberta Scholz Pinto Garcia Marcos Vinícius da Silva Edna Cleide Mendes Muricy Valdelene Sayuri Kohara Adriana Pardini Vicentini |
| author_sort | Kátia Cristina Dantas |
| collection | DOAJ |
| description | This case reports an immunocompetent 29-year-old woman with suspected pneumonia, suggestive of fungal infection. Immunoblotting analysis reactivity againstHistoplasma capsulatum and Paracoccidioides brasiliensis were observed. Nested-PCR in blood employing species-specific primers was positive for H. capsulatum andCryptococcus neoformans. The evaluation of paucisymptomatic patients with positive results for H. capsulatum and C. neoformans could be relevant for the prevention as well as the possible evaluation of the reactivated quiescent foci. In conclusion, the associated methodology may have contributed to the monitoring endogenous reactivation of these diseases. |
| first_indexed | 2024-04-13T14:14:07Z |
| format | Article |
| id | doaj.art-585dc6479add419187505abcb60fbeeb |
| institution | Directory Open Access Journal |
| issn | 1678-9199 |
| language | English |
| last_indexed | 2024-04-13T14:14:07Z |
| publishDate | 2014-10-01 |
| publisher | SciELO |
| record_format | Article |
| series | Journal of Venomous Animals and Toxins including Tropical Diseases |
| spelling | doaj.art-585dc6479add419187505abcb60fbeeb2022-12-22T02:43:42ZengSciELOJournal of Venomous Animals and Toxins including Tropical Diseases1678-91992014-10-0120010.1186/1678-9199-20-36S1678-91992014000200507Importance of the association of molecular and immunological diagnosis in immunocompetent patient with Histoplasma capsulatum and Cryptoccocus neoformans infection: a case reportKátia Cristina DantasRoseli Santos de FreitasRoberta Scholz Pinto GarciaMarcos Vinícius da SilvaEdna Cleide Mendes MuricyValdelene Sayuri KoharaAdriana Pardini VicentiniThis case reports an immunocompetent 29-year-old woman with suspected pneumonia, suggestive of fungal infection. Immunoblotting analysis reactivity againstHistoplasma capsulatum and Paracoccidioides brasiliensis were observed. Nested-PCR in blood employing species-specific primers was positive for H. capsulatum andCryptococcus neoformans. The evaluation of paucisymptomatic patients with positive results for H. capsulatum and C. neoformans could be relevant for the prevention as well as the possible evaluation of the reactivated quiescent foci. In conclusion, the associated methodology may have contributed to the monitoring endogenous reactivation of these diseases.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200507&lng=en&tlng=enImmunocompetent individualsNested PCRImmunoblottingFungal infectionsBlood fluid |
| spellingShingle | Kátia Cristina Dantas Roseli Santos de Freitas Roberta Scholz Pinto Garcia Marcos Vinícius da Silva Edna Cleide Mendes Muricy Valdelene Sayuri Kohara Adriana Pardini Vicentini Importance of the association of molecular and immunological diagnosis in immunocompetent patient with Histoplasma capsulatum and Cryptoccocus neoformans infection: a case report Journal of Venomous Animals and Toxins including Tropical Diseases Immunocompetent individuals Nested PCR Immunoblotting Fungal infections Blood fluid |
| title | Importance of the association of molecular and immunological diagnosis in immunocompetent patient with Histoplasma capsulatum and Cryptoccocus neoformans infection: a case report |
| title_full | Importance of the association of molecular and immunological diagnosis in immunocompetent patient with Histoplasma capsulatum and Cryptoccocus neoformans infection: a case report |
| title_fullStr | Importance of the association of molecular and immunological diagnosis in immunocompetent patient with Histoplasma capsulatum and Cryptoccocus neoformans infection: a case report |
| title_full_unstemmed | Importance of the association of molecular and immunological diagnosis in immunocompetent patient with Histoplasma capsulatum and Cryptoccocus neoformans infection: a case report |
| title_short | Importance of the association of molecular and immunological diagnosis in immunocompetent patient with Histoplasma capsulatum and Cryptoccocus neoformans infection: a case report |
| title_sort | importance of the association of molecular and immunological diagnosis in immunocompetent patient with histoplasma capsulatum and cryptoccocus neoformans infection a case report |
| topic | Immunocompetent individuals Nested PCR Immunoblotting Fungal infections Blood fluid |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992014000200507&lng=en&tlng=en |
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