Prior treatment with oxaliplatin-containing regimens and higher total bilirubin levels are risk factors for neutropenia and febrile neutropenia in patients with gastric or esophagogastric junction cancer receiving weekly paclitaxel and ramucirumab therapy: a single center retrospective study

Prior treatment with oxaliplatin-containing regimens and higher total bilirubin levels are risk factors for neutropenia and febrile neutropenia in patients with gastric or esophagogastric junction cancer receiving weekly paclitaxel and ramucirumab therapy: a single center retrospective study

Abstract Background Weekly paclitaxel + ramucirumab (wPTX + RAM) therapy is recommended as the standard second-line chemotherapy regimen for unresectable advanced/recurrent gastric cancer (GC) or esophagogastric junction cancer. Recent subgroup analysis of the RAINBOW trial revealed a higher frequen...

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Bibliographic Details
Main Authors: Katsuhiko Nara, Takehito Yamamoto, Hiroharu Yamashita, Koichi Yagi, Tappei Takada, Yasuyuki Seto, Hiroshi Suzuki
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Cancer
Subjects:
Weekly paclitaxel + ramucirumab
Febrile neutropenia
Oxaliplatin
Total bilirubin
Gastric/Esophagogastric cancer
Online Access:https://doi.org/10.1186/s12885-023-11469-y

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