The hardness of the vessel wall in patients with arterial hypertension
The article deals with the role of the hardness of the vessel wall in the pathogenesis of arterial hypertension and its complications and cardiovascular mortality. We discussed the factors increasing the hardness of the vessel wall, such as age, blood pressure level, atherosclerosis, smoking and dia...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
IP Morozov P.V.
2015-06-01
|
| Series: | Системные гипертензии |
| Subjects: | |
| Online Access: | https://syst-hypertension.ru/2075-082X/article/viewFile/29073/pdf |
| _version_ | 1818891228015493120 |
|---|---|
| author | O D Ostroumova A I Kochetkov I I Kopchenov T F Guseva O V Bondarec |
| author_facet | O D Ostroumova A I Kochetkov I I Kopchenov T F Guseva O V Bondarec |
| author_sort | O D Ostroumova |
| collection | DOAJ |
| description | The article deals with the role of the hardness of the vessel wall in the pathogenesis of arterial hypertension and its complications and cardiovascular mortality. We discussed the factors increasing the hardness of the vessel wall, such as age, blood pressure level, atherosclerosis, smoking and diabetes mellitus. We showed the indicators reflecting the status of the vascular wall and which could play a role of markers of increased risk of cardiovascular complications. We reviewed the data concerning the improvement of the parameters of the hardness of the vessel wall under the influence of antihypertensive therapy using the angiotensin II type 1 receptor blocker - candesartan. We discussed the possible mechanisms of the candesartan influence on the elastic properties of the vessels. We stressed that the effect on the hardness of the arteries on using antihypertensive drugs, even within the same class, was different, which, apparently, was associated with the difference in the pharmacokinetic properties. |
| first_indexed | 2024-12-19T17:37:28Z |
| format | Article |
| id | doaj.art-585f377b05f54ffeb9ff2d2618c3fcf5 |
| institution | Directory Open Access Journal |
| issn | 2075-082X 2542-2189 |
| language | Russian |
| last_indexed | 2024-12-19T17:37:28Z |
| publishDate | 2015-06-01 |
| publisher | IP Morozov P.V. |
| record_format | Article |
| series | Системные гипертензии |
| spelling | doaj.art-585f377b05f54ffeb9ff2d2618c3fcf52022-12-21T20:12:17ZrusIP Morozov P.V.Системные гипертензии2075-082X2542-21892015-06-01122434826174The hardness of the vessel wall in patients with arterial hypertensionO D Ostroumova0A I Kochetkov1I I Kopchenov2T F Guseva3O V Bondarec4A.I.Evdokimov Moscow State Medical and Dental University of the Ministry of Health of the Russian Federation; I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian FederationA.I.Evdokimov Moscow State Medical and Dental University of the Ministry of Health of the Russian FederationA.I.Evdokimov Moscow State Medical and Dental University of the Ministry of Health of the Russian FederationA.I.Evdokimov Moscow State Medical and Dental University of the Ministry of Health of the Russian FederationA.I.Evdokimov Moscow State Medical and Dental University of the Ministry of Health of the Russian FederationThe article deals with the role of the hardness of the vessel wall in the pathogenesis of arterial hypertension and its complications and cardiovascular mortality. We discussed the factors increasing the hardness of the vessel wall, such as age, blood pressure level, atherosclerosis, smoking and diabetes mellitus. We showed the indicators reflecting the status of the vascular wall and which could play a role of markers of increased risk of cardiovascular complications. We reviewed the data concerning the improvement of the parameters of the hardness of the vessel wall under the influence of antihypertensive therapy using the angiotensin II type 1 receptor blocker - candesartan. We discussed the possible mechanisms of the candesartan influence on the elastic properties of the vessels. We stressed that the effect on the hardness of the arteries on using antihypertensive drugs, even within the same class, was different, which, apparently, was associated with the difference in the pharmacokinetic properties.https://syst-hypertension.ru/2075-082X/article/viewFile/29073/pdfarterial hypertensiondiabetes mellitusthe hardness of the vessel wallpulse ware velocityangiotensin ii receptor blockerscan- desartan |
| spellingShingle | O D Ostroumova A I Kochetkov I I Kopchenov T F Guseva O V Bondarec The hardness of the vessel wall in patients with arterial hypertension Системные гипертензии arterial hypertension diabetes mellitus the hardness of the vessel wall pulse ware velocity angiotensin ii receptor blockers can- desartan |
| title | The hardness of the vessel wall in patients with arterial hypertension |
| title_full | The hardness of the vessel wall in patients with arterial hypertension |
| title_fullStr | The hardness of the vessel wall in patients with arterial hypertension |
| title_full_unstemmed | The hardness of the vessel wall in patients with arterial hypertension |
| title_short | The hardness of the vessel wall in patients with arterial hypertension |
| title_sort | hardness of the vessel wall in patients with arterial hypertension |
| topic | arterial hypertension diabetes mellitus the hardness of the vessel wall pulse ware velocity angiotensin ii receptor blockers can- desartan |
| url | https://syst-hypertension.ru/2075-082X/article/viewFile/29073/pdf |
| work_keys_str_mv | AT odostroumova thehardnessofthevesselwallinpatientswitharterialhypertension AT aikochetkov thehardnessofthevesselwallinpatientswitharterialhypertension AT iikopchenov thehardnessofthevesselwallinpatientswitharterialhypertension AT tfguseva thehardnessofthevesselwallinpatientswitharterialhypertension AT ovbondarec thehardnessofthevesselwallinpatientswitharterialhypertension AT odostroumova hardnessofthevesselwallinpatientswitharterialhypertension AT aikochetkov hardnessofthevesselwallinpatientswitharterialhypertension AT iikopchenov hardnessofthevesselwallinpatientswitharterialhypertension AT tfguseva hardnessofthevesselwallinpatientswitharterialhypertension AT ovbondarec hardnessofthevesselwallinpatientswitharterialhypertension |