Small extracellular vesicles deliver osteolytic effectors and mediate cancer‐induced osteolysis in bone metastatic niche

Small extracellular vesicles deliver osteolytic effectors and mediate cancer‐induced osteolysis in bone metastatic niche

Abstract Extracellular vesicles (EVs) play critical roles in regulating bone metastatic microenvironment through mediating intercellular crosstalks. However, little is known about the contribution of EVs derived from cancer cells to the vicious cycle of bone metastasis. Here, we report a direct regu...

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Bibliographic Details
Main Authors: Qinyu Ma, Mengmeng Liang, Yutong Wu, Ce Dou, Jianzhong Xu, Shiwu Dong, Fei Luo
Format: Article
Language:English
Published: Wiley 2021-02-01
Series:Journal of Extracellular Vesicles
Subjects:
bone metastatic niche
cancer‐induced osteolysis
extracellular vesicles
miRNAs
Online Access:https://doi.org/10.1002/jev2.12068

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