Sleep architecture and emotional inhibition processing in adolescents hospitalized during a suicidal crisis
BackgroundSuicide is the second leading cause of death in adolescents. Sleep disturbances could alter inhibitory processes and contribute to dangerous behaviors in this critical developmental period. Adolescents in suicidal crisis have been shown to have lighter sleep compared to healthy controls. A...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-08-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.920789/full |
| _version_ | 1818517553123688448 |
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| author | Paniz Tavakoli Malika Lanthier Malika Lanthier Meggan Porteous Meggan Porteous Addo Boafo Joseph De Koninck Rebecca Robillard Rebecca Robillard |
| author_facet | Paniz Tavakoli Malika Lanthier Malika Lanthier Meggan Porteous Meggan Porteous Addo Boafo Joseph De Koninck Rebecca Robillard Rebecca Robillard |
| author_sort | Paniz Tavakoli |
| collection | DOAJ |
| description | BackgroundSuicide is the second leading cause of death in adolescents. Sleep disturbances could alter inhibitory processes and contribute to dangerous behaviors in this critical developmental period. Adolescents in suicidal crisis have been shown to have lighter sleep compared to healthy controls. Additionally, suicidal adolescents have lower neural resources mobilized by emotionally charged inhibition processing. The present exploratory study aimed to determine how sleep architecture in suicidal adolescents may relate to inhibition processing in response to emotional stimuli.MethodsTen adolescents between 12 and 17 years of age with a diagnosis of major depressive disorder and who attempted suicide were recruited while hospitalized for a suicidal crisis in a psychiatric inpatient unit. Event-related potentials (ERPs) were recorded prior to bedtime during a Go/NoGo task involving pictures of sad, happy, and neutral faces. Polysomnography was then recorded throughout the night. Pearson correlations were conducted to investigate how inhibition performance and ERP parameters reflecting inhibition processing (i.e., P3d and N2d derived from difference waveform calculated as NoGo minus Go trials) relate to sleep architecture.ResultsPoorer inhibition accuracy in response to emotional stimuli was significantly correlated with shorter REM sleep latency, higher REM sleep, and more frequent nocturnal awakenings. The P3d in response to sad faces was negatively correlated with NREM2 sleep and positively correlated with NREM3 sleep. No such association with the P3d was found for happy or neutral stimuli. There were no significant correlations for the N2d.ConclusionAltered sleep in adolescents with depression who are in a suicidal crisisis associated with behavioral inhibition difficulties and fewer neural resources mobilized by inhibitory processes in emotionally charged contexts. This highlights the importance of addressing sleep disturbances while managing suicidal crises in adolescents. |
| first_indexed | 2024-12-11T00:57:46Z |
| format | Article |
| id | doaj.art-5860d679c557497dace8e7e28b9d11e4 |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-12-11T00:57:46Z |
| publishDate | 2022-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-5860d679c557497dace8e7e28b9d11e42022-12-22T01:26:25ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402022-08-011310.3389/fpsyt.2022.920789920789Sleep architecture and emotional inhibition processing in adolescents hospitalized during a suicidal crisisPaniz Tavakoli0Malika Lanthier1Malika Lanthier2Meggan Porteous3Meggan Porteous4Addo Boafo5Joseph De Koninck6Rebecca Robillard7Rebecca Robillard8Sleep Research Unit, Institute of Mental Health Research at the Royal, University of Ottawa, Ottawa, ON, CanadaSleep Research Unit, Institute of Mental Health Research at the Royal, University of Ottawa, Ottawa, ON, CanadaSchool of Psychology, University of Ottawa, Ottawa, ON, CanadaSleep Research Unit, Institute of Mental Health Research at the Royal, University of Ottawa, Ottawa, ON, CanadaSchool of Psychology, University of Ottawa, Ottawa, ON, CanadaMental Health Program, Children’s Hospital of Eastern Ontario, Ottawa, ON, CanadaSchool of Psychology, University of Ottawa, Ottawa, ON, CanadaSleep Research Unit, Institute of Mental Health Research at the Royal, University of Ottawa, Ottawa, ON, CanadaSchool of Psychology, University of Ottawa, Ottawa, ON, CanadaBackgroundSuicide is the second leading cause of death in adolescents. Sleep disturbances could alter inhibitory processes and contribute to dangerous behaviors in this critical developmental period. Adolescents in suicidal crisis have been shown to have lighter sleep compared to healthy controls. Additionally, suicidal adolescents have lower neural resources mobilized by emotionally charged inhibition processing. The present exploratory study aimed to determine how sleep architecture in suicidal adolescents may relate to inhibition processing in response to emotional stimuli.MethodsTen adolescents between 12 and 17 years of age with a diagnosis of major depressive disorder and who attempted suicide were recruited while hospitalized for a suicidal crisis in a psychiatric inpatient unit. Event-related potentials (ERPs) were recorded prior to bedtime during a Go/NoGo task involving pictures of sad, happy, and neutral faces. Polysomnography was then recorded throughout the night. Pearson correlations were conducted to investigate how inhibition performance and ERP parameters reflecting inhibition processing (i.e., P3d and N2d derived from difference waveform calculated as NoGo minus Go trials) relate to sleep architecture.ResultsPoorer inhibition accuracy in response to emotional stimuli was significantly correlated with shorter REM sleep latency, higher REM sleep, and more frequent nocturnal awakenings. The P3d in response to sad faces was negatively correlated with NREM2 sleep and positively correlated with NREM3 sleep. No such association with the P3d was found for happy or neutral stimuli. There were no significant correlations for the N2d.ConclusionAltered sleep in adolescents with depression who are in a suicidal crisisis associated with behavioral inhibition difficulties and fewer neural resources mobilized by inhibitory processes in emotionally charged contexts. This highlights the importance of addressing sleep disturbances while managing suicidal crises in adolescents.https://www.frontiersin.org/articles/10.3389/fpsyt.2022.920789/fullsleepinhibitionsuicideemotional processingadolescenceevent related potentials |
| spellingShingle | Paniz Tavakoli Malika Lanthier Malika Lanthier Meggan Porteous Meggan Porteous Addo Boafo Joseph De Koninck Rebecca Robillard Rebecca Robillard Sleep architecture and emotional inhibition processing in adolescents hospitalized during a suicidal crisis Frontiers in Psychiatry sleep inhibition suicide emotional processing adolescence event related potentials |
| title | Sleep architecture and emotional inhibition processing in adolescents hospitalized during a suicidal crisis |
| title_full | Sleep architecture and emotional inhibition processing in adolescents hospitalized during a suicidal crisis |
| title_fullStr | Sleep architecture and emotional inhibition processing in adolescents hospitalized during a suicidal crisis |
| title_full_unstemmed | Sleep architecture and emotional inhibition processing in adolescents hospitalized during a suicidal crisis |
| title_short | Sleep architecture and emotional inhibition processing in adolescents hospitalized during a suicidal crisis |
| title_sort | sleep architecture and emotional inhibition processing in adolescents hospitalized during a suicidal crisis |
| topic | sleep inhibition suicide emotional processing adolescence event related potentials |
| url | https://www.frontiersin.org/articles/10.3389/fpsyt.2022.920789/full |
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