Is Helicobacter pylori Anyway Pathogen in Children?

Helicobacter pylori ( H. pylori ) infection is a continuous challenge for both gastroenterologists and pediatricians. The international guidelines regarding diagnostic and treatment pathways differ between adults and children. The pediatric guidelines are more restrictive because children are rarely...

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Main Authors: Marco Manfredi MD, PhD, Pierpacifico Gismondi MD, PhD, Silvia Iuliano MD
Format: Article
Language:English
Published: SAGE Publishing 2023-02-01
Series:Inquiry: The Journal of Health Care Organization, Provision, and Financing
Online Access:https://doi.org/10.1177/00469580231154650
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author Marco Manfredi MD, PhD
Pierpacifico Gismondi MD, PhD
Silvia Iuliano MD
author_facet Marco Manfredi MD, PhD
Pierpacifico Gismondi MD, PhD
Silvia Iuliano MD
author_sort Marco Manfredi MD, PhD
collection DOAJ
description Helicobacter pylori ( H. pylori ) infection is a continuous challenge for both gastroenterologists and pediatricians. The international guidelines regarding diagnostic and treatment pathways differ between adults and children. The pediatric guidelines are more restrictive because children are rarely affected by serious consequences, particularly in Western countries. Therefore, infected children should be treated only after a careful case-by-case evaluation by a pediatric gastroenterologist. In any case, recent studies are confirming an increasingly all-around pathological role of H. pylori even in asymptomatic children. For these reasons, following the current evidence, we feel that H. pylori -infected children could be treated starting in pre-adolescence, particularly in Eastern countries, because their stomachs have already begun to develop the biomarkers of gastric damage. Therefore, we believe that H. pylori is anyway pathogen in children. Nevertheless, the possible beneficial role of H. pylori in humans has not yet been conclusively disproved.
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spelling doaj.art-586478abe9f94fcf8821be518007ac3b2023-02-18T06:33:23ZengSAGE PublishingInquiry: The Journal of Health Care Organization, Provision, and Financing0046-95801945-72432023-02-016010.1177/00469580231154650Is Helicobacter pylori Anyway Pathogen in Children?Marco Manfredi MD, PhD0Pierpacifico Gismondi MD, PhD1Silvia Iuliano MD2Azienda USL-IRCCS di Reggio Emilia, Maternal and Child Department, Pediatric Unit, Sant’Anna Hospital, Castelnovo ne Monti, Reggio Emilia, ItalyWeek Hospital, Pietro Barilla Children’s Hospital, Azienda Ospedaliero-Universitaria di Parma, Parma, ItalyPediatric Gastroenterology, Pietro Barilla Children’s Hospital, Azienda Ospedaliero-Universitaria di Parma, Parma, ItalyHelicobacter pylori ( H. pylori ) infection is a continuous challenge for both gastroenterologists and pediatricians. The international guidelines regarding diagnostic and treatment pathways differ between adults and children. The pediatric guidelines are more restrictive because children are rarely affected by serious consequences, particularly in Western countries. Therefore, infected children should be treated only after a careful case-by-case evaluation by a pediatric gastroenterologist. In any case, recent studies are confirming an increasingly all-around pathological role of H. pylori even in asymptomatic children. For these reasons, following the current evidence, we feel that H. pylori -infected children could be treated starting in pre-adolescence, particularly in Eastern countries, because their stomachs have already begun to develop the biomarkers of gastric damage. Therefore, we believe that H. pylori is anyway pathogen in children. Nevertheless, the possible beneficial role of H. pylori in humans has not yet been conclusively disproved.https://doi.org/10.1177/00469580231154650
spellingShingle Marco Manfredi MD, PhD
Pierpacifico Gismondi MD, PhD
Silvia Iuliano MD
Is Helicobacter pylori Anyway Pathogen in Children?
Inquiry: The Journal of Health Care Organization, Provision, and Financing
title Is Helicobacter pylori Anyway Pathogen in Children?
title_full Is Helicobacter pylori Anyway Pathogen in Children?
title_fullStr Is Helicobacter pylori Anyway Pathogen in Children?
title_full_unstemmed Is Helicobacter pylori Anyway Pathogen in Children?
title_short Is Helicobacter pylori Anyway Pathogen in Children?
title_sort is helicobacter pylori anyway pathogen in children
url https://doi.org/10.1177/00469580231154650
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