‘Never change a winning team’: GPs’ perspectives on discontinuation of long-term antidepressants

Background Long-term antidepressant use, much longer than recommended by guidelines, can harm patients and generate unnecessary costs. Most antidepressants are prescribed by general practitioners (GPs) but it remains unclear why they do not discontinue long-term use. Aim To explore GPs’ views and ex...

Full description

Bibliographic Details
Main Authors: Van Leeuwen Ellen, Sibyl Anthierens, Mieke L. van Driel, An De Sutter, Evelien van den Branden, Thierry Christiaens
Format: Article
Language:English
Published: Taylor & Francis Group 2021-10-01
Series:Scandinavian Journal of Primary Health Care
Subjects:
Online Access:http://dx.doi.org/10.1080/02813432.2021.2006487
_version_ 1798034238395645952
author Van Leeuwen Ellen
Sibyl Anthierens
Mieke L. van Driel
An De Sutter
Evelien van den Branden
Thierry Christiaens
author_facet Van Leeuwen Ellen
Sibyl Anthierens
Mieke L. van Driel
An De Sutter
Evelien van den Branden
Thierry Christiaens
author_sort Van Leeuwen Ellen
collection DOAJ
description Background Long-term antidepressant use, much longer than recommended by guidelines, can harm patients and generate unnecessary costs. Most antidepressants are prescribed by general practitioners (GPs) but it remains unclear why they do not discontinue long-term use. Aim To explore GPs’ views and experiences of discontinuing long-term antidepressants, barriers and facilitators of discontinuation and required support. Design and setting Qualitative study in Belgian GPs. Method 20 semi-structured face-to-face interviews with GPs. Interviews were analysed thematically. Results The first theme, ‘Success stories’ describes three strong motivators to discontinue antidepressants: patient health issues, patient requests and a new positive life event. Second, not all GPs consider long-term antidepressant use a ‘problem’ as they perceive antidepressants as effective and safe. GPs’ main concern is the risk of relapse. Third, GPs foresee that discontinuation of antidepressants is not an easy and straightforward process. GPs weigh up whether they have the necessary skills and whether it is worth the effort to start this process. Conclusion Discontinuation of long-term antidepressants is a difficult and uncertain process for GPs, especially in the absence of a facilitating life-event or patient demand. The absence of a compelling need for discontinuation and fear of relapse of symptoms in a stable patient are important barriers for GPs when considering discontinuation. In order to increase GPs’ motivation to discontinue long-term antidepressants, more emphasis on the futility of the actual effect and on potential harms related to long-term use is needed.KEY POINTS Current awareness: Long-term antidepressant use, much longer than recommended by guidelines, can harm patients and generate unnecessary costs. Main statements:  • Discontinuation of long-term antidepressants is a difficult and uncertain process for GPs.  • More emphasis on the futility of the actual effect of antidepressants and on potential harms related to long-term use is needed.
first_indexed 2024-04-11T20:41:36Z
format Article
id doaj.art-586bf51ad3414196afa72c778204d9b2
institution Directory Open Access Journal
issn 0281-3432
1502-7724
language English
last_indexed 2024-04-11T20:41:36Z
publishDate 2021-10-01
publisher Taylor & Francis Group
record_format Article
series Scandinavian Journal of Primary Health Care
spelling doaj.art-586bf51ad3414196afa72c778204d9b22022-12-22T04:04:12ZengTaylor & Francis GroupScandinavian Journal of Primary Health Care0281-34321502-77242021-10-0139453354210.1080/02813432.2021.20064872006487‘Never change a winning team’: GPs’ perspectives on discontinuation of long-term antidepressantsVan Leeuwen Ellen0Sibyl Anthierens1Mieke L. van Driel2An De Sutter3Evelien van den Branden4Thierry Christiaens5Clinical Pharmacology Unit, Department of Basic and Applied Medical Sciences, Ghent UniversityFamily Medicine and Population, Health University of AntwerpFaculty of Medicine, Primary Care Clinical Unit, University of QueenslandDepartment of Family Medicine and Primary Health Care, Ghent UniversityGeneral practice “Het Spoor”Clinical Pharmacology Unit, Department of Basic and Applied Medical Sciences, Ghent UniversityBackground Long-term antidepressant use, much longer than recommended by guidelines, can harm patients and generate unnecessary costs. Most antidepressants are prescribed by general practitioners (GPs) but it remains unclear why they do not discontinue long-term use. Aim To explore GPs’ views and experiences of discontinuing long-term antidepressants, barriers and facilitators of discontinuation and required support. Design and setting Qualitative study in Belgian GPs. Method 20 semi-structured face-to-face interviews with GPs. Interviews were analysed thematically. Results The first theme, ‘Success stories’ describes three strong motivators to discontinue antidepressants: patient health issues, patient requests and a new positive life event. Second, not all GPs consider long-term antidepressant use a ‘problem’ as they perceive antidepressants as effective and safe. GPs’ main concern is the risk of relapse. Third, GPs foresee that discontinuation of antidepressants is not an easy and straightforward process. GPs weigh up whether they have the necessary skills and whether it is worth the effort to start this process. Conclusion Discontinuation of long-term antidepressants is a difficult and uncertain process for GPs, especially in the absence of a facilitating life-event or patient demand. The absence of a compelling need for discontinuation and fear of relapse of symptoms in a stable patient are important barriers for GPs when considering discontinuation. In order to increase GPs’ motivation to discontinue long-term antidepressants, more emphasis on the futility of the actual effect and on potential harms related to long-term use is needed.KEY POINTS Current awareness: Long-term antidepressant use, much longer than recommended by guidelines, can harm patients and generate unnecessary costs. Main statements:  • Discontinuation of long-term antidepressants is a difficult and uncertain process for GPs.  • More emphasis on the futility of the actual effect of antidepressants and on potential harms related to long-term use is needed.http://dx.doi.org/10.1080/02813432.2021.2006487mental healthantidepressantslong-term usediscontinuationqualitative researchgeneral practitioner
spellingShingle Van Leeuwen Ellen
Sibyl Anthierens
Mieke L. van Driel
An De Sutter
Evelien van den Branden
Thierry Christiaens
‘Never change a winning team’: GPs’ perspectives on discontinuation of long-term antidepressants
Scandinavian Journal of Primary Health Care
mental health
antidepressants
long-term use
discontinuation
qualitative research
general practitioner
title ‘Never change a winning team’: GPs’ perspectives on discontinuation of long-term antidepressants
title_full ‘Never change a winning team’: GPs’ perspectives on discontinuation of long-term antidepressants
title_fullStr ‘Never change a winning team’: GPs’ perspectives on discontinuation of long-term antidepressants
title_full_unstemmed ‘Never change a winning team’: GPs’ perspectives on discontinuation of long-term antidepressants
title_short ‘Never change a winning team’: GPs’ perspectives on discontinuation of long-term antidepressants
title_sort never change a winning team gps perspectives on discontinuation of long term antidepressants
topic mental health
antidepressants
long-term use
discontinuation
qualitative research
general practitioner
url http://dx.doi.org/10.1080/02813432.2021.2006487
work_keys_str_mv AT vanleeuwenellen neverchangeawinningteamgpsperspectivesondiscontinuationoflongtermantidepressants
AT sibylanthierens neverchangeawinningteamgpsperspectivesondiscontinuationoflongtermantidepressants
AT miekelvandriel neverchangeawinningteamgpsperspectivesondiscontinuationoflongtermantidepressants
AT andesutter neverchangeawinningteamgpsperspectivesondiscontinuationoflongtermantidepressants
AT evelienvandenbranden neverchangeawinningteamgpsperspectivesondiscontinuationoflongtermantidepressants
AT thierrychristiaens neverchangeawinningteamgpsperspectivesondiscontinuationoflongtermantidepressants